Spirolactams by a novel ipso-radical cyclisation and loss of aromaticity

DOI: 10.1016/S0040-4039(97)01362-2

Source and publish data:

Tetrahedron Letters p. 5985 - 5988 (1997)

Update date:2022-08-17

Topics:

Authors:

Boivin, Jean

Yousfi, Mohammed

Zard, Samir Z.

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Article abstract of DOI:10.1016/S0040-4039(97)01362-2

Spirolactams are obtained by ipso radical cyclisation when various substituted N-benzyl trichloroacetamides are subjected to the nickel powder/acetic acid reducing system.

Full text of DOI:10.1016/S0040-4039(97)01362-2

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