Non-stereospecific formation of 3α,7α,24-trihydroxy-5β-cholestan-26- oic acid during chenodeoxycholic acid biosynthesis

DOI: 10.1248/cpb.42.1536

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1536 - 1538 (1994)

Update date:2022-08-12

Topics:

Authors:

Kobayashi

Hagiwara

Morisaki

Yuri Yuri

Fujimoto

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Article abstract of DOI:10.1248/cpb.42.1536

Incubation of 3α,7α-dihydroxy-5β-cholestan-26-oic acid and its Δ²⁴- analog with rat liver homogenate produced a mixture of C-24,25 diastereoisomers of 3α,7α,24-trihydroxy-5β-cholestan-26-oic acid, a key intermediate of chenodeoxycholic acid biosynthesis.

Full text of DOI:10.1248/cpb.42.1536

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