Regioselective nitration of 3-acetylindole and its N-acyl and N-sulfonyl derivatives

DOI: 10.1016/S0040-4039(98)02636-7

Source and publish data:

Tetrahedron Letters p. 1117 - 1120 (1999)

Update date:2022-08-16

Topics:

Authors:

Ottoni, Olivia

Cruz, Rosimeire

Krammer, Norbert H.

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Article abstract of DOI:10.1016/S0040-4039(98)02636-7

3-Acetylindole reacts regioselectively with NO₂BF₄ in the presence of SnCl₄ to produce 3-acetyl-5-nitroindole or 3-acetyl-6-nitroindole, depending on the temperature, both in excellent yields.

Full text of DOI:10.1016/S0040-4039(98)02636-7

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