1300
J.-Q. Liu et al.
tion of State Key Laboratory of Phytochemistry and
Plant Resources in West China (P2008-ZZ05 and
P2010-ZZ14), and the Knowledge Innovation Program
of the CAS (Grant No. KSCX2-YW-G-038, 027, and
KSCX2-YW-R-194, 29, as well as KZCX2-XB2-15-03).
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Fig. 2. Selected HMBC and H-H COSY correlations of
1
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, and SW480 cell lines using the MTT assay. Com-
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1
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hibitory activities against all tested cells. Other com-
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7
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8 (Table II).
In our research, we found that the main compounds,
including brusatol, bruceine B, bruceine D, and yan-
danziolide A, from cultivated B. javanica were similar
to those from wild B. javanica. Furthermore, these
main compounds had significant antitumor effects in
the cytotoxicity assay. Therefore, in our opinion, this
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ACKNOWLEDGEMENTS
The project was financially supported by Founda-
Brucea javanica. Chem. Pharm. Bull., 32, 4698-4701 (1984).