Practical syntheses of the C12-C21 epothilone subunit via catalytic asymmetric reductions: Itsuno-Corey oxazaborolidine reduction and asymmetric Noyori hydrogenation

DOI: 10.1016/j.tetlet.2004.06.009

Source and publish data:

Tetrahedron Letters p. 5845 - 5847 (2004)

Update date:2022-08-17

Topics:

Authors:

Reiff, Emily A.

Nair, Sajiv K.

Narayan Reddy

Inagaki, Jun

Henri, John T.

Greiner, Jack F.

Georg, Gunda I.

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Article abstract of DOI:10.1016/j.tetlet.2004.06.009

Two practical catalytic asymmetric reductions to introduce the epothilone C15 stereocenter are described (Itsuno-Corey reduction and Noyori hydrogenation).

Full text of DOI:10.1016/j.tetlet.2004.06.009

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