Chloroiron(III)-5,10,15,20-tetraarylporphinate/N-methylimidazole catalyzed oxidation of androst-4-en-3,17-dione by cumene hydroperoxide

Article abstract of DOI:10.1016/S0040-4039(00)97030-8

The oxidation of androst-4-en-3,17-dione with cumene hydroperoxide, catalyzed by chloroiron(III)-5,10,15,20-tetraarylporphinate/N-methyl-imidazole systems, was studied under different reaction conditions. The chloroiron(III)-5,10,15,20-tetra(2,6-dichlorophenyl)porphinate/N-methy limidazole system in dichloromethane was found to be the most effective system for the aromatization of the A ring of androst-4-en-3,17-dione.