Asymmetric Catalytic Hydrogenation of α-Ketoesters Using New Chiral Ru(II)(AMPP) Complexes

Article abstract of DOI:10.1016/0957-4166(94)00338-C

Chiral bidentate amino(amido)phosphinephosphinite ligands (AMPP) have been used to synthesise new ruthenium bismethylallyl Ru(AMPP)(CH2C(CH3)CH2)2 and biscarboxylate Ru(AMPP)(OCOR)2 (R = CH3 or CF3) complexes.These complexes act as efficient catalyst precursors for the homogeneous asymmetric hydrogenation of α-ketoesters with enantiomeric excesses up to 79percent.