Rapid routes of synthesis of oligonucleotide conjugates from non-protected oligonucleotides and ligands possessing different nucleophilic or electrophilic functional groups

Article abstract of DOI:10.1080/15257770008045470

Optimized methods are described for post-synthetic conjugation of non-protected oligodeoxyribonucleotides to different ligands. Methods for the terminal functionalization of oligonucleotides by amino, sulfhydryl, thiophosphate or carboxyl groups using dif

Full text of DOI:10.1080/15257770008045470

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Nucleosides, Nucleotides and Nucleic
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Rapid Routes of Synthesis of
Oligonucleotide Conjugates from Non-
Protected Oligonucleotides and Ligands
Possessing Different Nucleophilic or
Electrophilic Functional Groups
Gunther N. Grimm a , Alexandre S. Boutorine a & Claude Helene a
a Laboratoire de Biophysique, INSERM U201 - CNRS UMR 8646,
Museum National d'Histoire Naturelle, 43 rue Cuvier, 7523 1, Paris
Cedex 05, France
Version of record first published: 17 Apr 2008.
To cite this article: Gunther N. Grimm , Alexandre S. Boutorine & Claude Helene (2000): Rapid
Routes of Synthesis of Oligonucleotide Conjugates from Non-Protected Oligonucleotides and Ligands
Possessing Different Nucleophilic or Electrophilic Functional Groups, Nucleosides, Nucleotides and
Nucleic Acids, 19:10-12, 1943-1965
To link to this article: http://dx.doi.org/10.1080/15257770008045470
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