Synlett p. 741 - 744 (2015)
Update date:2022-08-11
Topics:
Karami, Bahador
Farahi, Mahnaz
Banaki, Zohreh
A novel, environmentally friendly synthesis of 5,9-dihydro-pyrimido[5,4-e][1,2,4]triazolo[1,5-a]pyrimidine-6,8(4H,7H)-diones has been developed by using a one-pot condensation of 1,3-dimethylbarbituric acid, 3-amino-1H-1,2,4-triazoles, and aromatic aldehydes. The reactions were established based on green chemistry principles under catalyst- and solvent-free conditions.
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