Hindered Organoboron Groups in Organic Synthesis. 16. Preparation and Use of Lithium Ditriptylethylhydroborate for the Diastereoselective Reduction of Cyclohexanones

Article abstract of DOI:10.1016/0040-4039(91)80799-C

Preparations of lithium and potassium ditriptylethylhydroborates are outlined.The lithium salt reduces substituted cyclohexanones with diastereoselectivities comparable with the most selective reagents known, but with the advantages that low temperatures are not required and the corresponding borane is air stable and can be quantitatively recovered.