Studies on aryl H-phosphonates; Part 2: A general method for the preparation of alkyl H-phosphonate monoesters

Article abstract of DOI:10.1055/s-1995-3919

A simple and efficient synthetic method for the preparation of alkyl H-phosphonate monoesters has been developed. The method consists of transesterification of commercially available diphenyl H-phosphonate with an appropriate alcohol under mild conditions, followed by ammonolysis of the in situ formed dialkyl and alkyl phenyl H-phosphonates.