7 (2 Aminomethylphenylacetamido) 3 (1 carboxymethyltetrazol 5 ylthiomethyl)3 cephem 4 carboxylic acid

Article abstract of DOI:10.7164/antibiotics.29.1226

The synthesis of 7 (2 aminomethylphenylacetamido) 3 (1 carbomethyltetrazol 5 ylthiomethyl) 3 cephem 4 carboxylic acid (BL S786) is described and the antimicrobial activities are compared with cefazolin and cefamandole. The compound exhibits broad antimicrobial spectrum, produces high intramuscular blood levels in mice and demonstrates a high degree of therapeutic efficacy in experimental bacterial infections in rodents.