Tetrahedron p. 6635 - 6648 (1991)
Update date:2022-08-10
Topics:
Ihara, Masataka
Tokunaga, Yuji
Taniguchi, Nobuaki
Fukumoto, Keiichiro
A new approach for construction of the A/B ring system of steroids was developed by way of an intramolecular 1,3-dipolar cycloaddition of a nitrile oxide 4, followed by an incorporation of a C3 unit.A highly stereocontrolled synthesis of (+)-testosterone 1 was accomplished by this strategy. Key Words: Steroids, testosterone, 1,3-dipolar cycloaddition, nitrile oxide, chiral synthesis
View More
Doi:10.1016/S0960-894X(98)00076-6
(1998)Doi:10.1016/S0040-4039(98)02546-5
(1999)Doi:10.1246/cl.171216
(2018)Doi:10.1021/ja01551a042
(1958)Doi:10.1016/j.jallcom.2015.01.101
(2015)Doi:10.1021/ja974091k
(1998)
