Bioorganic and Medicinal Chemistry p. 6451 - 6460 (2004)
Update date:2022-08-24
Topics:
Yeager, Adam R.
Finney, Nathaniel S.
Chitin synthase (CS) is essential for fungal cell wall biosynthesis and is an attractive medicinal target. Expanded results from our efforts to develop mechanism based inhibitors of CS are presented here. Specifically, we describe uridine dimers linked by tartrate amides as potential pyrophosphate mimics.
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