
Tetrahedron Letters p. 5489 - 5492 (1998)
Update date:2022-08-16
Topics:
Lange, Gordon L.
Furlan, Lorena
MacKinnon, Mark C.
A highly regio- and stereoselective synthesis of the sesquiterpenoid trichodiene is reported. The approach requires only nine steps starting with a [2+2] photoaddition and employs the free radical fragmentation of an 'external' cyclobutane bond in a key step.
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