Carbohydrate Research p. 169 - 177 (1997)
Update date:2022-08-25
Topics:
Vachoud, Laurent
Zydowicz, Nathalie
Domard, Alain
The formation of N-acetyl chitosan gels in anacetic acid-water-propanediol solution was studied. Side reactions arising from the esterification of 1,2-propanediol by acetic anhydride, and hydrolysis of acetic anhydride were studied, as well as their possible role on the gel formation. The gels were studied by FTIR and 1H NMR spectroscopy. Independently of the initial acetylation degree of chitosan, a minimal acetylation degree is required for gelation (80%). The final acetylation degree of the gels increases with the molar ratio acetic anhydride/amine, but does not reach 100%. An increase in temperature favours the molecular mobility, inter- and intra-molecular hydrogen bondings and hydrophobic interactions, responsible for gelation which appears to depend on two parameters: a critical acetylation degree and a critical molecular weight allowing the aggregation of the polymer chains. The nature of the solvent used to avoid chitosan side reactions during gelation (ethanol or propanediol) does not influence the chemical structure of the gel but only the kinetics of gelation.
View MoreContact:+86-371-86058576
Address:NO.32, Jingsan Road, Zhengzhou, China
Onlychem (Jinan)Biotech Co.,Ltd
Contact:86-531-83175885
Address:No. 44, Honglou South Road, Jinan,China
Suzhou HeChuang Chemical Co.,Ltd.
Contact:+86-512-88800520
Address:No.9 Guanchao Rd,Changshu Advanced Materials Industy Park
HK Vast Medicinal Chemistry Int'l Group Limited(expird)
website:http://www.hkvast.com/
Contact:+86-15000309979
Address:NO.6,Lane 108,Qinzhou Road,Xuhui District,Shanghai
Shanghai Kangxin Chemical Co., Ltd
Contact:+86 21 60717227
Address:118,Ganbai Village,Waigang Town,Jiading District,Shanghai
Doi:10.1016/S0039-6028(01)01350-4
(2001)Doi:10.1021/i360008a012
(1963)Doi:10.1002/chem.200800293
(2008)Doi:10.1016/j.ejmech.2015.01.013
(2015)Doi:10.1039/c39820000696
(1982)Doi:10.1021/jo0159284
(2001)