A convenient synthesis of substituted pyrroles from esters of amino acids

Article abstract of DOI:10.1080/00397919408010197

A new simple synthesis of substituted pyrroles from alkyl, aryl or heteroaryl substituted α-amino acids is described. Esters of α-amino acids are first reacted with dimethyl acetylenedicarboxylate and in the in situ formed enamines are thereafter cyclized in presence of sodium methoxide to pyrroles.

Full text of DOI:10.1080/00397919408010197

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A Convenient Synthesis of
Substituted Pyrroles from
Esters of Amino Acids
Patrik Kolar a & Miha Tišler a
a Department of Chemistry, Faculty of Natural
Sciences and Technology, University of Ljubljana,
61000, Ljubljana, Slovenia
Published online: 23 Sep 2006.
To cite this article: Patrik Kolar & Miha Tišler (1994): A Convenient Synthesis of
Substituted Pyrroles from Esters of Amino Acids, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 24:13,
1887-1893
To link to this article: http://dx.doi.org/10.1080/00397919408010197
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