STRUCTURE OF THE STEROIDAL ALKALOID MULDAMINE AND ITS DEACETYL DERIVATIVE

Article abstract of DOI:10.1016/0031-9422(82)85214-X

Spectral techniques have established the structure of muldamine from Veratrum californicum as (22S,25S)-22,26-epiminocholest-5-ene-3β,16α-diol 16-acetate, instead of the C-nor-D-homo steroid structure previously suggested.Its deacetyl derivative seems to be identical with teinemine, the configuration of which at C-22 is therefore S and not R as previously reported.Key Word Index-Veratrum californicum; Liliaceae; steroidal alkaloid; muldamine; (22S,25S)-22,26-epiminocholest-5-ene-3β,16α-diol 16-acetate; deacetylmuldamine; teinemine; isoteinemine.