Further studies on the catalysis of hydrolysis and aminolysis of benzylpenicillin by metal chelates

DOI: 10.1002/jps.2600720402

Source and publish data:

Journal of Pharmaceutical Sciences p. 331 - 335 (1983)

Update date:2022-08-17

Topics:

Authors:

Tomida Tomida

Schwartz

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Article abstract of DOI:10.1002/jps.2600720402

It was suggested previously that the very rapid catalysis of benzylpenicillin hydrolysis and aminolysis by zinc ion and tris(hydroxymethyl)aminomethane (tromethamine) was mediated by a ternary complex in which the metal ion not only held the substrate and

Full text of DOI:10.1002/jps.2600720402

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