ISOMERIC HYDROPEROXYEUDESMANOLIDES FROM ARTEMISIA UMBELLIFORMIS

Article abstract of DOI:10.1016/S0031-9422(00)97692-1

Investigation of the aerial parts of Artemisia umbelliformis afforded the new eudesmanolides 5-desoxy-5-hydroperoxytelekin and 5-desoxy-5-hydroperoxy-5-epitelekin.A conformational study of the latter and some transformation products showed that these cis-decalin-type eudesmanolides exist in solution at room temperature as single preferred rotamers whose conformation depends on the substituent at C-5. - Key Word Index: Artemisia umbelliformis; Compositae, sesquiterpene lactones; hydroperoxides; cis-decalin derivatives; 5-desoxy-5-hydroperoxytelekin; 5-desoxy-5-hydroperoxy-5-epitelekin.