Molecules p. 871 - 884 (2002)
Update date:2022-08-11
Topics:
Pavlicic, Davorka
Koruznjak, Jasna Dogan
Banic-Tomisic, Zrinka
Karminski-Zamola, Grace
Three new heterocyclic substituted dianilides, namely 3-chloro-5-[1-(p- fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]thieno-[3,2-b]thiophene-2-carboxy-p- fluoroanilide (8), 1,2-bis{5-[2-(p-fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]- 2-thienyl}ethene (13) and 6-chloro-2-{2-[3-chloro-2-(p-fluorophenyl-carbamoyl)- 5-thieno[3,2-b]thienyl]-2-ethoxycarbonylethenyl}thieno[3,2-b] furan-5-carboxy-p-fluoroanilide (20) were prepared by multistep synthesis. The prepared dianilides are of particular interest for their potential to serve as the planar heteroaromatic core of DNA intercalators or groove binders.
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