Further Cembranoid Derivatives from the Red Sea Soft Corals Alcyonium flaccidum and Lobophytum crassum

Article abstract of DOI:10.1021/jo00331a003

The cembranoid content of two soft corals has been investigated.Three compounds were isolated from Alcyonium flaccidum and were found to be cembrene-C (1), sarcophytol-B (2), and the as yet unreported 11,12-epoksy-13-hydroxy-14-acetoxycembrene-C (3), which was named flaccidoxide. From Lobophytum crassum, another soft coral whose chemical content was found to change remarkably with place of collection, were isolated two new 13-hydroxylobolides (7 and 8) in addition to lobolide (6), and their structures were characterized.The ¹³C NMR spectra of all the above compounds were assigned.