BIFUNCTIONAL CHIRAL SYNTHONS VIA MICROBIOLOGICAL METHODS. 2. OPTICALLY-ACTIVE α-HYDROXY ALDEHYDES.

DOI: 10.1016/S0040-4039(00)85875-X

Source and publish data:

Tetrahedron Letters p. 5489 - 5492 (1982)

Update date:2022-08-10

Topics:

Authors:

Takaishi, Yoshihisa

Yang, Yuh-Lin

DiTullio, Dennis

Sih, Charles J.

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Article abstract of DOI:10.1016/S0040-4039(00)85875-X

A versatile chemical-microbiological approach has been developed for the preparation of chiral α-hydroxy aldehydes via stereoselective reduction of the corresponding α-keto thioacetals or via optical resolution of the racemic α-acetoxy esters.

Full text of DOI:10.1016/S0040-4039(00)85875-X

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