Synthetic Communications p. 1461 - 1465 (1996)
Update date:2022-08-16
Topics:
Ferri?o, Sergio
López-Tapia, Francisco
Salgado-Zamora, Héctor
Ethynyl cerium chloride, prepared in situ from ethynyl magnesium bromide or lithium acetylide and anhydrous cerium chloride efficiently added to 13-ethyl-3-methoxy-gona-3,5-diene-17-one 2. Aqueous HCl hydrolysis of intermediate enol ether 3 gave high yields of norgestrel 4.
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