Radical clock substrate probes and kinetic isotope effect studies of the hydroxylation of hydrocarbons by methane monooxygenase

Article abstract of DOI:10.1021/ja00056a018

Four mechanistic probes, trans-2-phenylmethylcyclopropane (1), 2,2-diphenylmethylcyclopropane (2), trans-1,2-dimethylcyclopropane (3), and bicyclo[2.1.0]pentane (4), were used as substrates to investigate the possible formation of radical intermediates in