FIRST STEREOSELECTIVE SYNTHESIS OF D-AMINO ACID N-ALKYL AMIDE CATALYZED BY D-AMINOPEPTIDASE

Article abstract of DOI:10.1016/S0040-4020(01)89103-1

The first stereoselective synthesis of D-amino acid N-alkyl amides was achieved by the use of D-aminopeptidase from Ochrobactrum anthropi.The enzyme immobilized by urethane prepolymer PU-6 catalyzed aminolysis reaction of racemic amino acid esters in organic solvents.