Asymmetric hydrosilylation of dihydrofurans by use of palladium-MOP catalyst

Article abstract of DOI:10.1016/S0040-4039(00)77607-6

Catalytic asymmetric hydrosilylation of dihydrofuran derivatives including 7-oxabicyclo[2.2.1]heptenes with trichlorosilane proceeded in the presence of 0.1 mol % of palladium catalyst bearing (R)-2-methoxy-2'-diphenyl-phosphino-1,1'-binaphthyl ((R)-MOP) to give the corresponding hydrosilylation products of up to 95% ee. A regio-selective opening of the bicyclic system gave a highly functionalized cyclohexane in an optically active form.