Chemistry of Heterocyclic Compounds p. 838 - 841 (1983)
Update date:2022-08-16
Topics:
Nikolaev, V.N.
Yakimovich, S.I.
Koshmina, N.V.
Zelenin, K.N.
Alekseev, V.V.
et al.
The product of condensation of thiobenzhydrazide with methyl acetoacetate and its α-alkyl-substituted homologs have the structure of the corresponding 2,3-dihydro-1,3,4-thiadiazoles; only the derivative of α-isopropylacetoacetic acid ester has the open hydrazone form.The products of the reaction of thiobenzhydrazide with the methyl ester of 2-oxocyclopentane- and 2-oxocyclohexanecarboxylic acid are mixtures of enehydrazine and thiadiazoline forms; the percentage of the latter decreases in polar solvents.
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