Bioorganic and Medicinal Chemistry Letters p. 2379 - 2384 (1999)
Update date:2022-08-25
Topics:
James, David A.
Swamy, Narasimha
Paz, Nancy
Hanson, Robert N.
Ray, Rahul
A tetraphenylporphyrin-C11-β-estradiol conjugate has been synthesized. Competitive binding assay of the conjugate with estrogen receptor (ER)-ligand-binding domain showed that the conjugate binds specifically to the protein with high affinity. Potential use of this conjugate to selectively deliver cytotoxic porphyrins to ER-positive cells in various carcinomas is discussed.
View More
Weifang Jahwa Chemical Co.,Ltd
Contact:0086-536-8897731,8897730
Address:No.5166 East Dongfeng Street,Weifang,Shandong,China
Shanghai Egoal Chemical Co.,Ltd
Contact:+86-21-50333091
Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
Contact:0086-357-6662688
Address:Zhaocheng town, Hongtong County, Linfen City, Shanxi Province
shijiazhuang shuanglian chemical industry co.,ltd
Contact:0311-82190302
Address:Luquan Intersection , Shijiazhuang--Taiyuan Expressway，Shijiazhuang City
Contact:86 513 85512619
Address:Rm.1306, Building A, Wenfeng Mansion,168 Gongnong Road, Nantong Jiangsu China
Doi:10.1021/om500904k
(2014)Doi:10.1016/j.cplett.2004.02.069
(2004)Doi:10.1021/jf052792s
(2006)Doi:10.1002/hlca.19430260503
(1943)Doi:10.1021/ja00531a045
(1980)Doi:10.1021/jo00142a014
(1982)
