Chlorofluoroacetyl chloride

Base Information

• Chemical Name: Chlorofluoroacetyl chloride
• CAS No.: 359-32-0
• Molecular Formula: C2HCl2FO
• Molecular Weight: 130.934
• Hs Code.: 2915900090
• European Community (EC) Number: 801-832-4
• DSSTox Substance ID: DTXSID90957317
• Mol file: 359-32-0.mol

Synonyms:Chlorofluoroacetyl chloride;359-32-0;2-chloro-2-fluoroacetyl chloride;Chlorofluoroacetylchloride;Acetyl chloride, chlorofluoro-;chloro(fluoro)acetyl chloride;C2HCl2FO;C2-H-Cl2-F-O;SCHEMBL836624;DTXSID90957317;VZJVRCWSIVAASQ-UHFFFAOYSA-N;MFCD01861134;alpha-chloro-alpha-fluoroacetyl chloride;FT-0650890;EN300-378606;A823049

Chemical Property of Chlorofluoroacetyl chloride

Chemical Property:

• Vapor Pressure: 122.44mmHg at 25°C
• Refractive Index: 1.4
• Boiling Point: 71.695 °C at 760 mmHg
• PSA: 17.07000
• Density: 1.5 g/cm³
• LogP: 1.28620
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 129.9388482
• Heavy Atom Count: 6
• Complexity: 64.6

Purity/Quality:

98%Min ^*data from raw suppliers

ChlorofluoroacetylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34-36/37/38
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(=O)Cl)(F)Cl

Technology Process of Chlorofluoroacetyl chloride

There total 3 articles about Chlorofluoroacetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.5%

ethoxyflurane (310-71-4) → 1-fluoroethane (353-36-6) + chloroethane (75-00-3) + chlorofluoroacetyl fluoride (359-34-2) + chlorofluoroacetyl chloride (359-32-0)

Guidance literature:

With aluminium trichloride; for 1.58333h;

DOI:10.1016/S0022-1139(00)82333-7

Reference yield:

Trichloroethylene (79-01-6) → phosgene (75-44-5) + dichloroacethyl chloride (79-36-7) + dichloroacetyl fluoride (359-31-9) + chlorofluoroacetyl chloride (359-32-0)

Guidance literature:

Produkt₅:Oxalylchlorid;Produkt₆:Pentachloraethan;Produkt₇:Hexachlorbuten;

DOI:10.1021/ja01593a039

Reference yield:

hypofluorous acid trifluoromethyl ester (373-91-1) + Trichloroethylene (79-01-6) → phosgene (75-44-5) + dichloroacethyl chloride (79-36-7) + 1,2,2-trichloro-1,2-difluoroethane (354-15-4) + chlorofluoroacetyl chloride (359-32-0) + 1-fluoro-2-trifluoromethyl-1,1,2-trichloroethane (94720-90-8) + Chloro-trifluoromethoxy-acetyl chloride

Guidance literature:

With oxygen; at 20.6 ℃; Rate constant; Mechanism; various pressures and temperatures;

upstream raw materials:

ethoxyflurane

hypofluorous acid trifluoromethyl ester

Trichloroethylene

Downstream raw materials:

dichlorofluoroacetic acid

2-chloro-2-fluoro-N-phenylacetamide

N--N-methyl-anilin

ethyl chlorofluoroacetate

Refernces

• 1、 Hudlicky, Milos. "REACTION OF ALKYL 2-CHLORO-1,1,2-TRIFLUOROETHYL ETHERS WITH LEWIS ACIDS". . p. 349 - 354. Retrieved 2007/10/02.