2-Chloro-1,1,2-trifluoroethyl ethyl ether

Base Information

• Chemical Name: 2-Chloro-1,1,2-trifluoroethyl ethyl ether
• CAS No.: 310-71-4
• Molecular Formula: C4H6ClF3O
• Molecular Weight: 162.539
• Hs Code.: 2909199090
• European Community (EC) Number: 684-157-6
• UNII: 36IC8E3484
• DSSTox Substance ID: DTXSID00953123
• Nikkaji Number: J404.104F
• Wikidata: Q27115954
• Mol file: 310-71-4.mol

Synonyms:2-Chloro-1,1,2-trifluoroethyl ethyl ether;310-71-4;2-chloro-1-ethoxy-1,1,2-trifluoroethane;Ethoxyflurane;2-Chloro-1,1,2-trifluoroethylethylether;Ethyl 2-chloro-1,1,2-trifluoroethyl ether;UNII-36IC8E3484;Ethane, 2-chloro-1-ethoxy-1,1,2-trifluoro-;36IC8E3484;2-chloro-1-ethoxy-1,1,2-trifluoro-ethane;SCHEMBL2003790;CHEBI:34266;WOKICPFFJCXEDW-UHFFFAOYSA-;DTXSID00953123;MFCD00018849;AKOS006228194;BS-43798;C2862;CS-0320447;FT-0611674;D89522;Q27115954

Chemical Property of 2-Chloro-1,1,2-trifluoroethyl ethyl ether

Chemical Property:

• Vapor Pressure: 78.5mmHg at 25°C
• Refractive Index: 1.3479
• Boiling Point: 85.1 °C at 760 mmHg
• Flash Point: 5.3 °C
• PSA: 9.23000
• Density: 1.259 g/cm³
• LogP: 2.15010
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 162.0059270
• Heavy Atom Count: 9
• Complexity: 87.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Chloro-1,1,2-trifluoroethyl Ethyl Ether ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F
• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(C(F)Cl)(F)F

Technology Process of 2-Chloro-1,1,2-trifluoroethyl ethyl ether

There total 2 articles about 2-Chloro-1,1,2-trifluoroethyl ethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol (64-17-5) + Chlorotrifluoroethylene (79-38-9,9036-80-0) → ethoxyflurane (310-71-4)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/ja01184a076

Reference yield:

Chlorotrifluoroethylene (79-38-9,9036-80-0) + sodium ethanolate (141-52-6) → ethoxyflurane (310-71-4)

Guidance literature:

Reference yield: 57.5%

ethoxyflurane (310-71-4) → 1-fluoroethane (353-36-6) + chloroethane (75-00-3) + chlorofluoroacetyl fluoride (359-34-2) + chlorofluoroacetyl chloride (359-32-0)

Guidance literature:

With aluminium trichloride; for 1.58333h;

DOI:10.1016/S0022-1139(00)82333-7

upstream raw materials:

ethanol

Chlorotrifluoroethylene

sodium ethanolate

Downstream raw materials:

(1-chloro-ethyl)-(2-chloro-1,1,2-trifluoro-ethyl)-ether

(2-chloro-ethyl)-(2-chloro-1,1,2-trifluoro-ethyl)-ether

ethyl chlorofluoroacetate

1-fluoroethane

Refernces

• 1、 Nguyen, Thoai. "TRANSFORMATION D'OXYDES D'ALKYLES ET DE POLYFLUOROALKYLES PAR LES ACIDES DE LEWIS. INFLUENCE DES RADICAUX ALKYLES.". . p. 95 - 106. Retrieved 2007/10/02.