Amoxycilloic Acid (Mixture of Diastereomers)

Base Information

• Chemical Name: Amoxycilloic Acid (Mixture of Diastereomers)
• CAS No.: 57414-05-8
• Molecular Formula: C15H21N3O4S
• Molecular Weight: 339.41
• Mol file: 57414-05-8.mol

Synonyms:

Chemical Property of Amoxycilloic Acid (Mixture of Diastereomers)

Chemical Property:

• Melting Point: 203-205°C (dec.)
• Boiling Point: 664.4±55.0 °C(Predicted)
• PKA: 2.00±0.60(Predicted)
• Density: 1.313±0.06 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Purity/Quality:

99% ^*data from raw suppliers

AmoxycilloicAcid(MixtureofDiastereomers) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Amoxycilloic Acid (Mixture of Diastereomers)

There total 5 articles about Amoxycilloic Acid (Mixture of Diastereomers) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

(6R)-amoxycilloic acid → (S)-2-{[(R)-2-Amino-2-(4-hydroxy-phenyl)-acetylamino]-methyl}-5,5-dimethyl-thiazolidine-4-carboxylic acid (57414-05-8)

Guidance literature:

at 80 ℃; for 96h;

Reference yield:

amoxicillin (26787-78-0,81030-75-3) → Thiazole-4-carboxylic acid (3973-08-8) + 5,5-Dimethyl-4,5-dihydro-thiazole-4-carboxylic acid (740742-98-7) + formic acid (64-18-6) + glycolic Acid (79-14-1) + 1,5-pentanedioic acid (110-94-1) + Adipic acid (124-04-9) + tartronic acid (80-69-3) + glyceric acid (473-81-4,118916-26-0) + oxamic acid (471-47-6) + succinic acid (110-15-6) + C5H8O6S (1378848-02-2) + pisolithin A (15573-67-8) + C9H10N2O4 + C9H12N2O5S + C8H10N2O6S + C9H14N2O7S + C9H12N2O6S + C8H10N2O4S + C10H12N2O7S + C15H21N3O4S (1356020-01-3,57414-05-8) + C15H18N2O4S + C14H21N3O3S + C8H12N2O4S + C8H10N2O5S + C6H10O7S + C6H7NO4S + C6H11NO3S + C6H9NO3S + oxalic acid (144-62-7,97993-78-7) + acetic acid (64-19-7,77671-22-8) + propionic acid (802294-64-0,79-09-4) + 2-oxo-propionic acid (127-17-3) + tartaric acid (87-69-4,138508-61-9) + 6-aminopenicillanic acid (551-16-6) + benzoic acid (65-85-0,8013-63-6) + Glyoxilic acid (298-12-4) + 2-hydroxy-3-(4-hydroxyphenyl)pyrazine + 2-butenedioic acid (6915-18-0,26099-09-2) + butyric acid (107-92-6) + (4S)-2t-{(R)-[(R)-2-amino-2-(4-hydroxy-phenyl)-acetylamino]-carboxy-methyl}-5,5-dimethyl-thiazolidine-4r-carboxylic acid (57457-65-5) + 4-hydroxy-benzoic acid (99-96-7)

Guidance literature:

With Ru/CNT; sodium hydroxide; for 8h; Reagent/catalyst; Electrolysis;

DOI:10.1016/j.cattod.2019.06.039

Reference yield:

amoxicillin (26787-78-0,81030-75-3) → (5R)-amoxilloic acid (178738-48-2,1356020-01-3,57414-05-8) + the pennicilloic acid of amoxycillin (42947-63-7)

Guidance literature:

With potassium hydroxide; In water; Reagent/catalyst;

DOI:10.21577/0103-5053.20180087

upstream raw materials:

amoxicillin

Refernces

• 1、 Paula, Marcos V.,Barros, Amanda L.,Wanderley, Kaline A.,De Sá, Gilberto F.,Eberlin, Marcos,Soares, Thereza A.,Alves, Severino Alves. "Metal organic frameworks for selective degradation of amoxicillin in biomedical wastes". . p. 2127 - 2136. Retrieved 2018/09/29.
• 2、 Yongxin, Zhu,Roets, Eugene,Busson, Roger,Janssen, Gerard,Hoogmartens, Jos. "Preparation of some potential impurities of ampicillin and amoxicillin". . p. 67 - 72. Retrieved 2007/10/03.