p-Phenoxystyrene

Base Information

• Chemical Name: p-Phenoxystyrene
• CAS No.: 4973-29-9
• Molecular Formula: C14H12 O
• Molecular Weight: 196.249
• Hs Code.: 2909309090
• European Community (EC) Number: 225-620-0
• NSC Number: 158435
• DSSTox Substance ID: DTXSID30198000
• Nikkaji Number: J203.216C
• Wikidata: Q83070762
• Mol file: 4973-29-9.mol

Synonyms:1-phenoxy-4-vinylbenzene;4973-29-9;4-PHENOXYSTYRENE;p-Phenoxystyrene;1-ethenyl-4-phenoxybenzene;Benzene, 1-ethenyl-4-phenoxy-;EINECS 225-620-0;NSC158435;SCHEMBL354205;DTXSID30198000;AMY32048;MFCD00026066;AKOS016010439;NSC 158435;NSC-158435;AS-58134;CS-0158020;FT-0619377;O10432;EN300-1861811;A871733

Chemical Property of p-Phenoxystyrene

Chemical Property:

• Vapor Pressure: 0.00239mmHg at 25°C
• Melting Point: 71°C
• Refractive Index: 1.6020
• Boiling Point: 115-117°C 3mm
• Flash Point: 128.9°C
• PSA: 9.23000
• Density: 1.055g/cm³
• LogP: 4.12190
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 196.088815002
• Heavy Atom Count: 15
• Complexity: 186

Purity/Quality:

99% ^*data from raw suppliers

1-Phenoxy-4-vinylbenzene 95+% ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CC1=CC=C(C=C1)OC2=CC=CC=C2

Technology Process of p-Phenoxystyrene

There total 19 articles about p-Phenoxystyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-phenoxy benzaldehyde (67-36-7) + Methyltriphenylphosphonium bromide (1779-49-3) → 4-phenoxystyrene (4973-29-9)

Guidance literature:

Methyltriphenylphosphonium bromide; With sodium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

4-phenoxy benzaldehyde; In tetrahydrofuran; at 0 - 20 ℃; for 18h; Inert atmosphere;

DOI:10.1021/jacs.1c00884

Reference yield: 88.0%

4-Bromodiphenyl ether (101-55-3) + tri-n-butyl(vinyl)tin (7486-35-3) → 4-phenoxystyrene (4973-29-9)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; tri-tert-butyl phosphine; In toluene; at 20 ℃; for 48h;

DOI:10.1021/ja020012f

Reference yield: 83.0%

Triethoxyvinylsilane (78-08-0) + 4-phenoxyiodobenzene (2974-94-9) → 4-phenoxystyrene (4973-29-9)

Guidance literature:

With sodium hydroxide; In methanol; water; at 100 ℃; for 10h; Sealed tube;

DOI:10.1002/ejoc.201400162

upstream raw materials:

1-(4-phenoxyphenyl)ethyl alcohol

bis-[1-(4-phenoxy-phenyl)-ethyl]-ether

2-(4-phenyloxyphenyl)ethyl alcohol

meta-nitrophenol

Downstream raw materials:

4-(methoxycarbonyl)benzyl alcohol

phenyl(4-vinylphenyl)sulfane

2-(4-phenyloxyphenyl)ethyl alcohol

2-(4-phenoxyphenyl)acetaldehyde

Refernces

• 1、 Zhou, Min-Jie,Zhang, Lei,Liu, Guixia,Xu, Chen,Huang, Zheng. "Site-Selective Acceptorless Dehydrogenation of Aliphatics Enabled by Organophotoredox/Cobalt Dual Catalysis". supporting information. p. 16470 - 16485. Retrieved 2021/10/20.
• 2、 Cong, Fei,Wei, Yongliang,Tang, Pingping. "Combining photoredox and silver catalysis for azidotrifluoromethoxylation of styrenes". supporting information. p. 4473 - 4476. Retrieved 2018/05/03.