Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoic acid

Base Information Edit
  • Chemical Name:2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoic acid
  • CAS No.:289686-70-0
  • Molecular Formula:C12H10F6O2
  • Molecular Weight:300.201
  • Hs Code.:
  • European Community (EC) Number:690-867-7
  • DSSTox Substance ID:DTXSID70431524
  • Wikidata:Q72447378
  • Mol file:289686-70-0.mol
2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoic acid

Synonyms:289686-70-0;2-(3,5-bis(trifluoromethyl)phenyl)-2-methylpropanoic acid;2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoic acid;2-(3,5-bis(trifluoroMethyl)phenyl)-2-Methyl propanoic acid;MFCD09032572;2-(3,5-Bis-trifluoromethyl-phenyl)-;2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropionic acid;2-(3,5-Bis-trifluoromethyl-phenyl)-2-methyl-propionic acid;SCHEMBL4028192;DTXSID70431524;ORLKRFYFNMCQIG-UHFFFAOYSA-N;Benzeneacetic acid, alpha,alpha-dimethyl-3,5-bis(trifluoromethyl)-;AKOS015964568;SB12449;AC-29247;AS-18966;SY060401;CS-0099348;EN300-7409832;A854125;2-(3,5-bis(trifluoromethyl)phenyl)-2-methylpropanoicacid;2-(3,5-bis-trifluoromethylphenyl)-2-methyl-propionic acid;2-(3,5-Bis-trifluoromethylphenyl)-2-methylpropionic acid;2-(3,5-bistrifluoromethyl-phenyl)-2-methyl propionic acid;alpha,alpha-Dimethyl-3,5-bis(trifluoromethyl)benzeneacetic Acid;Not available;2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoic acid

Suppliers and Price of 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoic acid
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 2-?(3,?5-?Bis(trifluoromethyl)?phenyl)?-?2-?methylpropanoicAcid
  • 1g
  • $ 105.00
  • Chemenu
  • 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoicacid 95+%
  • 1000g
  • $ 2240.00
  • Chemenu
  • 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoicacid 95+%
  • 500g
  • $ 736.00
  • Biosynth Carbosynth
  • 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropionic acid
  • 5 g
  • $ 130.00
  • Biosynth Carbosynth
  • 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropionic acid
  • 25 g
  • $ 475.00
  • Biosynth Carbosynth
  • 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropionic acid
  • 10 g
  • $ 230.00
  • Biosynth Carbosynth
  • 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropionic acid
  • 2 g
  • $ 84.00
  • Biosynth Carbosynth
  • 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropionic acid
  • 1 g
  • $ 65.00
  • Ambeed
  • 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoicacid 95%
  • 5g
  • $ 58.00
  • Ambeed
  • 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoicacid 95%
  • 1g
  • $ 19.00
Total 91 raw suppliers
Chemical Property of 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoic acid Edit
Chemical Property:
  • Melting Point:105.5-107℃ 
  • Boiling Point:232.5±35.0 °C(Predicted) 
  • PKA:4.06±0.14(Predicted) 
  • PSA:37.30000 
  • Density:1.378±0.06 g/cm3(Predicted) 
  • LogP:4.08640 
  • Storage Temp.:Sealed in dry,Room Temperature 
  • XLogP3:4.1
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:8
  • Rotatable Bond Count:2
  • Exact Mass:300.05849853
  • Heavy Atom Count:20
  • Complexity:349
Purity/Quality:

98% *data from raw suppliers

2-?(3,?5-?Bis(trifluoromethyl)?phenyl)?-?2-?methylpropanoicAcid *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(C)(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)C(=O)O
  • Uses 2-?(3,?5-?Bis(trifluoromethyl)?phenyl)?-?2-?methylpropanoic Acid is a reagent used in the synthesis of NK1/NK3 receptor antagonists used in the treatment of depression.
Technology Process of 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoic acid

There total 13 articles about 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
methyl 2-(3,5-bis(trifluoromethyl)phenyl)-2-methylpropanoate; With lithium hydroxide; water; In tetrahydrofuran; methanol; at 20 ℃; for 72h;
With hydrogenchloride; In water;
Guidance literature:
With trifluorormethanesulfonic acid; In dichloromethane; water; at 20 ℃; for 2h; under 22501.8 Torr;
DOI:10.1021/jo0523666
Post RFQ for Price