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Erythritol

Base Information Edit
  • Chemical Name:Erythritol
  • CAS No.:149-32-6
  • Deprecated CAS:10030-58-7,188346-77-2,868541-49-5,882981-67-1,1646188-83-1,1798874-12-0,2075830-99-6,909878-64-4,2584414-71-9,188346-77-2,868541-49-5,882981-67-1
  • Molecular Formula:C4H10O4
  • Molecular Weight:122.121
  • Hs Code.:2905499000
  • European Community (EC) Number:205-737-3
  • NSC Number:760400,8099
  • UNII:RA96B954X6
  • DSSTox Substance ID:DTXSID6043919
  • Nikkaji Number:J43.360H
  • Wikipedia:Erythritol
  • Wikidata:Q421873
  • RXCUI:1369563
  • Metabolomics Workbench ID:38233
  • ChEMBL ID:CHEMBL349605
  • Mol file:149-32-6.mol
Erythritol

Synonyms:Erythritol

Suppliers and Price of Erythritol
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
Total 241 raw suppliers
Chemical Property of Erythritol Edit
Chemical Property:
  • Appearance/Colour:white crystals or powder 
  • Vapor Pressure:1.26E-05mmHg at 25°C 
  • Melting Point:118-120 °C(lit.) 
  • Refractive Index:1.536 
  • Boiling Point:330 °C at 760 mmHg 
  • PKA:13.9(at 25℃) 
  • Flash Point:208.8 °C 
  • PSA:80.92000 
  • Density:1.43 g/cm3 
  • LogP:-2.30720 
  • Storage Temp.:-20°C 
  • Solubility.:H2O: 0.1?g/mL, clear to almost clear, colorless 
  • Water Solubility.:soluble 
  • XLogP3:-2.3
  • Hydrogen Bond Donor Count:4
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:3
  • Exact Mass:122.05790880
  • Heavy Atom Count:8
  • Complexity:48
Purity/Quality:

98% *data from raw suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes: Xi:Irritant;
     
  • Statements: R36/37/38:; 
  • Safety Statements: S26:; S36:; 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Chemical Classes:Other Uses -> Food Additives
  • Canonical SMILES:C(C(C(CO)O)O)O
  • Isomeric SMILES:C([C@H]([C@H](CO)O)O)O
  • Recent ClinicalTrials:Consumption of Oral Artificial Sweeteners on Platelet Aggregation and Polyol Excretion
  • Recent NIPH Clinical Trials:Study on the cooking methods of high-amylose rice 'Koshi-no-kaori' for suppressed blood glucose elevation
  • Sources Naturally occurring in plants, fermented foods, and biological fluids of humans and animals.
  • Chemical Composition and Structure Erythritol has a chemical formula C4H10O4 and is a four-carbon sugar alcohol. It occurs as a white anhydrous crystalline powder.
  • Uses Sweetener:
    Utilized as a low-calorie sweetener in various food and beverage products.

    Potential Health Benefits:
    Studied for potential health benefits, including its effect on glucose and insulin levels, weight management, and oral health.

    Production:
    Used in the production of various consumer products such as beverages, personal care items, and pharmaceuticals.
  • Mechanism of Action Erythritol is absorbed quickly and excreted unchanged in urine. It does not affect glucose or insulin levels and may promote gut hormone release.[1]
  • History and Development Traces of erythritol found in blackstrap molasses residue in the 1950s. Commercial production began in the early 2000s. FDA and EU approvals granted in the early and mid-2000s. In 2019, the global erythritol market transactions reached 70,400 tons equivalent to US$198.3 million, projected to rise to US$310 million by 2026.[1]
  • Production Methods Primarily produced by fermentation using yeast strains such as Yarrowia lipolytica. Chemical synthesis methods are available but less favored due to low efficiency.[3]
  • References [1] From the culture broth to the erythritol crystals: an opportunity for circular economy
    DOI 10.1007/s00253-021-11355-2
    [2] Erythritol: An In-Depth Discussion of Its Potential to Be a Beneficial Dietary Component
    DOI 10.3390/nu15010204
    [3] Enhancing erythritol production from crude glycerol in a wild-type Yarrowia lipolytica by metabolic engineering
    DOI 10.3389/fmicb.2022.1054243
Technology Process of Erythritol

There total 250 articles about Erythritol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With potassium permanganate; dihydrogen peroxide; In water; acetone; at 0 ℃; for 2h; Temperature; Inert atmosphere; Green chemistry;
DOI:10.1039/c5ra01646k
Guidance literature:
With ruthenium-carbon composite; hydrogen; In water; at 215 ℃; for 1.5h; under 39003.9 Torr; Reagent/catalyst; Catalytic behavior; Autoclave;
DOI:10.1039/c6ra27524a
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