2-hydroxy-5-fluoridechalcone

Base Information

Chemical Name:2-hydroxy-5-fluoridechalcone
CAS No.:1371535-38-4
Molecular Formula:C₁₅H₁₁FO₂
Molecular Weight:242.25
Hs Code.:

Synonyms:2-hydroxy-5-fluoridechalcone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-hydroxy-5-fluoridechalcone

Chemical Property:

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Technology Process of 2-hydroxy-5-fluoridechalcone

There total 1 articles about 2-hydroxy-5-fluoridechalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 347-54-6
5-fluoro-2-hydroxybenzaldehyde

: 98-86-2
acetophenone

: 1371535-38-4
2-hydroxy-5-fluoridechalcone

Guidance literature:: With sodium hydroxide; In methanol; at 20 ℃; for 4h;
DOI:10.1089/ars.2012.4909

Reference yield: 98.0%

: 67-56-1
methanol

: 3377-71-7
N-benzylindole

: 1371535-38-4
2-hydroxy-5-fluoridechalcone

: 1-benzyl-3-(6-fluoro-2-methoxy-2-phenylchroman-4-yl)-1H-indole

Guidance literature:: With trifluorormethanesulfonic acid; at 35 ℃; for 12h; diastereoselective reaction; Green chemistry;
DOI:10.1039/c8ra02481b

Reference yield: 94.0%

: 3335-86-2,114581-75-8,124508-46-9
3-hydroxy-1-methyl-indolin-2-one

: 1371535-38-4
2-hydroxy-5-fluoridechalcone

: 7'-fluoro-1-methyl-2'-phenyl-5'H-spiro[indoline-3,4'-[2,5]methanobenzo[d][1,3]dioxepin]-2-one

Guidance literature:: With trifluorormethanesulfonic acid; In ethyl acetate; at 35 ℃; for 24h; diastereoselective reaction;
DOI:10.1039/c7cc05813f