Technology Process of methyl {2-[4-(propyloxy)-2-(trifluoromethyl)phenyl]-5-pyrimidinyl}acetate
There total 6 articles about methyl {2-[4-(propyloxy)-2-(trifluoromethyl)phenyl]-5-pyrimidinyl}acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
silver benzoate; triethylamine;
Reflux;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium phosphate / tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 120 °C / Inert atmosphere; Microwave
2: water; lithium hydroxide / tetrahydrofuran / 1 h / 20 °C
3: thionyl chloride / 2 h / Reflux
4: diethyl ether / 20 °C
5: triethylamine; silver benzoate / Reflux
With
potassium phosphate; thionyl chloride; water; silver benzoate; triethylamine; lithium hydroxide;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; 1,4-dioxane; diethyl ether; water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium phosphate / tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 120 °C / Inert atmosphere; Microwave
2: water; lithium hydroxide / tetrahydrofuran / 1 h / 20 °C
3: thionyl chloride / 2 h / Reflux
4: diethyl ether / 20 °C
5: triethylamine; silver benzoate / Reflux
With
potassium phosphate; thionyl chloride; water; silver benzoate; triethylamine; lithium hydroxide;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; 1,4-dioxane; diethyl ether; water;
