Difluoroketene ethyl(trimethylsilyl)acetal

Base Information

• Chemical Name: Difluoroketene ethyl(trimethylsilyl)acetal
• CAS No.: 167308-39-6
• Molecular Formula: C₇H₁₄F₂O₂Si
• Molecular Weight: 196.269
• DSSTox Substance ID: DTXSID301228612
• Nikkaji Number: J820.752F

Synonyms:Difluoroketene ethyl(trimethylsilyl)acetal;RCQZKYGTAGIDLZ-UHFFFAOYSA-N;DTXSID301228612;167308-39-6;[(1-Ethoxy-2,2-difluoroethenyl)oxy]trimethylsilane

Chemical Property of Difluoroketene ethyl(trimethylsilyl)acetal

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 196.07311254
• Heavy Atom Count: 12
• Complexity: 171

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(=C(F)F)O[Si](C)(C)C

Technology Process of Difluoroketene ethyl(trimethylsilyl)acetal

There total 1 articles about Difluoroketene ethyl(trimethylsilyl)acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloro-trimethyl-silane (75-77-4) + ethyl trifluoroacetate, (383-63-1) → ethyltrimethylsilyl-2,2-difluoroketene acetal (167308-39-6) + α-(trimethylsilyl)difluoroacetic acid ethyl ester (205865-67-4)

Guidance literature:

With tetrabutylammomium bromide; triethylamine; In acetonitrile; at 0 ℃; Electrochemical reaction; Pb cathode, C anode;

DOI:10.1021/jo990571d

Reference yield: 10.0%

benzaldehyde (100-52-7) + ethyltrimethylsilyl-2,2-difluoroketene acetal (167308-39-6) → ethyl 2,2-difluoro-3-hydroxy-3-phenylpropanoate (92207-60-8)

Guidance literature:

With titanium tetrachloride; In dichloromethane; pentane; at -78 - 20 ℃;

DOI:10.1021/jo990571d

Reference yield:

Benzyloxyacetyl chloride (19810-31-2) + ethyltrimethylsilyl-2,2-difluoroketene acetal (167308-39-6) → 4-benzyloxy-2,2-difluoro-3-oxo-butyric acid ethyl ester

Guidance literature:

With copper(l) chloride; In various solvent(s); at 50 ℃; for 0.5h;

DOI:10.1016/S0040-4039(00)01744-5

upstream raw materials:

chloro-trimethyl-silane

ethyl trifluoroacetate,

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 167308-39-6 ethyltrimethylsilyl-2,2-difluoroketene acetal

Send

Send

Metric Ton KG G Pound L ML

Send

Send