Benzoic trimethylacetic anhydride

Base Information

• Chemical Name: Benzoic trimethylacetic anhydride
• CAS No.: 19820-60-1
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.241
• Mol file: 19820-60-1.mol

Synonyms:Benzoic trimethylacetic anhydride

Chemical Property of Benzoic trimethylacetic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of Benzoic trimethylacetic anhydride

There total 8 articles about Benzoic trimethylacetic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzoyl chloride (98-88-4) + Trimethylacetic acid (75-98-9) → Benzoic trimethylacetic anhydride (19820-60-1) + 2,2-dimethylpropanoic anhydride (1538-75-6) + benzoic acid anhydride (93-97-0)

Guidance literature:

With P₄-VP; In dichloromethane; at 0 ℃; for 0.166667h; Yield given. Yields of byproduct given;

DOI:10.1016/S0040-4039(00)85100-X

Reference yield:

pivalaldehyde (630-19-3) → Benzoic trimethylacetic anhydride (19820-60-1) + 2,2-dimethylpropanoic anhydride (1538-75-6)

Guidance literature:

Multi-step reaction with 2 steps

1: trichloroisocyanuric acid / dichloromethane / 20 °C / Inert atmosphere

2: triethylamine / 0 °C / Inert atmosphere

With trichloroisocyanuric acid; triethylamine; In dichloromethane;

DOI:10.1039/C6NJ02625G

Reference yield:

pivaloyl chloride (3282-30-2) + benzoic acid (65-85-0,8013-63-6) → Benzoic trimethylacetic anhydride (19820-60-1) + 2,2-dimethylpropanoic anhydride (1538-75-6)

Guidance literature:

With triethylamine; at 0 ℃; Inert atmosphere;

DOI:10.1039/C6NJ02625G

upstream raw materials:

pivaloyl chloride

thallium benzoate

carbon monoxide

benzenediazonium tetrafluoroborate

Downstream raw materials:

benzaldehyde

benzoic acid

Trimethylacetic acid

3,6-di-O-benzoyl-1,2-O-isopropylidene-α-D-glucofuranose

Refernces

• 1、 -. "DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF". Paragraph 0534-0535; 0698-0699. . Retrieved 2020/12/13.
• 2、 Gaspa, Silvia,Amura, Ida,Porcheddu, Andrea,De Luca, Lidia. "Anhydrides from aldehydes or alcohols via oxidative cross-coupling". supporting information. p. 931 - 939. Retrieved 2017/02/10.