2-(allyloxy)-N-methoxy-N-methylacetamide

Base Information

• Chemical Name: 2-(allyloxy)-N-methoxy-N-methylacetamide
• CAS No.: 1120309-29-6
• Molecular Formula: C₇H₁₃NO₃
• Molecular Weight: 159.185
• Mol file: 1120309-29-6.mol

Synonyms:2-(allyloxy)-N-methoxy-N-methylacetamide

Chemical Property of 2-(allyloxy)-N-methoxy-N-methylacetamide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

N-Methoxy-N-methyl-2-prop-2-enoxyacetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(allyloxy)-N-methoxy-N-methylacetamide

There total 5 articles about 2-(allyloxy)-N-methoxy-N-methylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-(allyloxy)acetic acid (22577-14-6) + N,O-dimethylhydroxylamine*hydrochloride (6638-79-5) → 2-(allyloxy)-N-methoxy-N-methylacetamide (1120309-29-6)

Guidance literature:

2-(allyloxy)acetic acid; With 4-methyl-morpholine; isobutyl chloroformate; In dichloromethane; at -15 ℃; for 1.5h;

N,O-dimethylhydroxylamine*hydrochloride; In dichloromethane; at 0.2 ℃; for 16.25h;

DOI:10.1021/ol8029142

Reference yield: 66.0%

2-bromo-N-methoxy-N-methyl-acetamide (134833-83-3) + allyl alcohol (107-18-6) → 2-(allyloxy)-N-methoxy-N-methylacetamide (1120309-29-6)

Guidance literature:

With potassium carbonate; toluene; at 30 ℃; for 2h; Large scale;

DOI:10.1021/op500351q

Reference yield:

2-(allyloxy)acetic acid (22577-14-6) + N,0-dimethylhydroxylamine (1117-97-1) → 2-(allyloxy)-N-methoxy-N-methylacetamide (1120309-29-6)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tetlet.2011.02.043

upstream raw materials:

N,O-dimethylhydroxylamine*hydrochloride

2-(allyloxy)acetic acid

N,0-dimethylhydroxylamine

2-bromo-N-methoxy-N-methyl-acetamide