4-Methoxy-2,3,5,6-tetramethylphenol

Base Information

• Chemical Name: 4-Methoxy-2,3,5,6-tetramethylphenol
• CAS No.: 19587-93-0
• Molecular Formula: C11H16O2
• Molecular Weight: 180.247
• Hs Code.: 2909500000
• DSSTox Substance ID: DTXSID40558777
• Nikkaji Number: J401.776E
• Wikidata: Q82441193
• Mol file: 19587-93-0.mol

Synonyms:4-METHOXY-2,3,5,6-TETRAMETHYLPHENOL;19587-93-0;SCHEMBL18090614;DTXSID40558777;G72315

Chemical Property of 4-Methoxy-2,3,5,6-tetramethylphenol

Chemical Property:

• PSA: 29.46000
• LogP: 2.63440
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 180.115029749
• Heavy Atom Count: 13
• Complexity: 154

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=C(C(=C1O)C)C)OC)C

Technology Process of 4-Methoxy-2,3,5,6-tetramethylphenol

There total 5 articles about 4-Methoxy-2,3,5,6-tetramethylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

Duroquinone (527-17-3,70128-24-4) + phosphorous acid trimethyl ester (121-45-9) → polymethyl-1-hydroxy-4-methoxybenzene (19587-93-0)

Guidance literature:

DOI:10.1021/jo961039i

Reference yield: 44.0%

methanol (67-56-1) + 4-methoxy-phenol (150-76-5) → 1-hydroxy-4-methoxy-2-methylbenzene (5307-05-1) + polymethyl-1-hydroxy-4-methoxybenzene (19587-93-0) + hydroquinone (123-31-9,8027-02-9) + 1,4-dimethoxybezene (150-78-7)

Guidance literature:

vanadium oxide compounds; In cyclohexane; at 340 ℃; for 4h; Product distribution; Kinetics; other catalysts, other time, other temperature;

Reference yield:

Durohydroquinone (527-18-4) + sodium ethanolate (141-52-6) + methyl iodide (74-88-4) → polymethyl-1-hydroxy-4-methoxybenzene (19587-93-0)

Guidance literature:

With ethanol; Erhitzen auf dem Dampfbad;

DOI:10.1021/ja01276a020

upstream raw materials:

3-chloromethyl-4-methoxy-2,5,6-trimethyl-phenol

Duroquinone

phosphorous acid trimethyl ester

methanol

Downstream raw materials:

4,4-dimethoxy-2,3,5,6-tetramethylcyclohexa-2,5-dien-1-one

4-methoxy-4-(4-methoxy-2,3,5,6-tetramethyl-phenoxy)-2,3,5,6-tetramethyl-cyclohexa-2,5-dienone

4-ethoxy-4-methoxy-2,3,5,6-tetramethyl-cyclohexa-2,5-dienone

4-methoxy-2,3,5,6-tetramethylphenoxyl radical