1-Propanone, 3-(dimethylamino)-1,2-diphenyl-

Base Information

• Chemical Name: 1-Propanone, 3-(dimethylamino)-1,2-diphenyl-
• CAS No.: 22563-99-1
• Molecular Formula: C17H19NO
• Molecular Weight: 253.344
• Mol file: 22563-99-1.mol

Synonyms:[2-(dimethylamino)-1-(phenyl)ethyl]-(phenyl)-ketone;3-dimethylamino-1,2-diphenyl-propan-1-one;1-dimethylamino-2,3-diphenylpropane-3-one;3-Dimethylamino-1,2-diphenyl-propan-1-on;3-Dimethylamino-1.2-diphenyl-propanon-(1);3-N,N-Dimethylamino-1,2-diphenylethan-2-on;

Chemical Property of 1-Propanone, 3-(dimethylamino)-1,2-diphenyl-

Chemical Property:

• PSA: 20.31000
• LogP: 3.21470

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Propanone, 3-(dimethylamino)-1,2-diphenyl-

There total 12 articles about 1-Propanone, 3-(dimethylamino)-1,2-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

phenyl benzyl ketone (451-40-1) + bis-(dimethylamino)methane (51-80-9) → 3-dimethylamino-1,2-diphenyl-propan-1-one (22563-99-1)

Guidance literature:

In methanol; for 48h; 9 kbar;

Reference yield: 67.0%

bis-(dimethylamino)methane (51-80-9) + 1-trimethylsilyloxy-1,2-diphenylethylene (72223-17-7) → 1,2-diphenylprop-2-en-1-one (4452-11-3) + 3-dimethylamino-1,2-diphenyl-propan-1-one (22563-99-1)

Guidance literature:

With Chloroiodomethane; In dimethyl sulfoxide; for 80h; Yields of byproduct given; Ambient temperature;

DOI:10.1246/bcsj.55.534

Reference yield: 43.0%

1,2-diphenyl-3-(N,N-dimethylamino)-2-propen-1-one (140866-59-7) → 1,2-diphenylprop-2-en-1-one (4452-11-3) + 3-dimethylamino-1,2-diphenyl-propan-1-one (22563-99-1)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1016/S0040-4020(01)85083-3

upstream raw materials:

phenyl benzyl ketone

dimethyl amine

1,2-diphenylprop-2-en-1-one

3-(Dimethylamino)-1,2-diphenyl-2-propen-1-on

Downstream raw materials:

1,4,5-triphenyl-1H-pyrazole

1,3,4-triphenyl-4,5-dihydro-1H-pyrazole

1-Acetamino-1.1-diacetyl-3-phenyl-butyrophenon

1-Acetamino-1-acetyl-3-phenyl-butyrophenon-carbonsaeure-⁽¹⁾-methylester