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Cas Database

Name	Sodium Pyruvate	EINECS	204-024-4
CAS No.	113-24-6	Density	1.267 g/cm³
PSA	57.20000	LogP	-1.67470
Solubility	water: 100 mg/mL	Melting Point	>300 °C(lit.)
Formula	C₃H₃NaO₃	Boiling Point	165 °C at 760 mmHg
Molecular Weight	110.045	Flash Point	54.3 °C
Transport Information	N/A	Appearance	White to slightly yellow crystalline powder
Safety	36/37/39-26-24/25	Risk Codes	36/37/38
Molecular Structure		Hazard Symbols	Xi
Synonyms	Propanoicacid, 2-oxo-, sodium salt (9CI);Pyruvic acid, sodium salt (7CI,8CI);Sodiumpyruvate;Sodium a-ketopropionate;	Article Data	22

Sodium Pyruvate Synthetic route

: 127-17-3
2-oxo-propionic acid

: 113-24-6
sodium pyruvate

Conditions

Conditions	Yield
With sodium formate In ethyl acetate	97%
With sodium acetate In ethyl acetate	94%
With sodium hydroxide; ethanol; water

: 79-41-4
poly(methacrylic acid)

: 113-24-6
sodium pyruvate

Conditions

Conditions	Yield
Stage #1: poly(methacrylic acid) With ozone In methanol; dichloromethane at -78℃; Stage #2: With dimethylsulfide In methanol; dichloromethane at -78 - 20℃; Stage #3: With sodium hydroxide In water	92%

: 97-64-3, 2676-33-7
ethyl 2-hydroxypropionate

: 113-24-6
sodium pyruvate

Conditions

Conditions	Yield
Stage #1: ethyl 2-hydroxypropionate With 9-azabicyclo<3.3.1>nonane-N-oxyl; dihydrogen peroxide In ethyl acetate at 10 - 40℃; for 3h; Stage #2: With sodium carbonate In water; ethyl acetate at 20℃; for 1h; pH=3 - 4; Reagent/catalyst; Temperature;	55%

: 56-41-7
L-alanin

: 114-76-1
sodium phenylphyruvate

A: 150-30-1
Phenylalanine

B: 113-24-6
sodium pyruvate

Conditions

Conditions	Yield
With acetate buffer; N(1+)C5His2C16; PL(1+)2C16; copper(II) perchlorate In water at 30℃; for 48h; Kinetics;

: 21593-77-1, 49621-03-6
S-allyl cysteine

A: 2179-57-9
diallyl disulphide

B: 539-86-6
allicin

C: 29418-05-1
bis-2-propenyl thiosulfonate

D: 113-24-6
sodium pyruvate

Conditions

Conditions	Yield
With nitrogen(II) oxide In water for 24h; Ambient temperature; Yield given. Yields of byproduct given;

: 44300-97-2
sodium enol pyruvate

: 113-24-6
sodium pyruvate

Conditions

Conditions	Yield
With sodium hydroxide; iodine; potassium iodide In water at 25℃; Rate constant; Equilibrium constant; other base as reagents;
With phosphate buffer; iodine; potassium iodide at 11℃; Equilibrium constant; Further Variations:; Temperatures; enolization;

: 43165-43-1
sodium pyruvate hydrate

: 113-24-6
sodium pyruvate

Conditions

Conditions	Yield
With sodium hydroxide In water at 25℃; Rate constant; Equilibrium constant; other bases or acids reagents;
With phosphate buffer; iodine; potassium iodide at 11℃; Equilibrium constant; Further Variations:; Temperatures; hydration;

: 312-85-6
sodium lactate

: 113-24-6
sodium pyruvate

Conditions

Conditions	Yield
With sodium hydroxide; lead(II) nitrate In water Product distribution; modified platinum electrode by lead ad-atoms, effect of pyruvate concentration;
With sodium ruthenate(VI); hexacyanoferrate(III); sodium perchlorate; sodium hydroxide at 30℃; Kinetics; Mechanism;

: 5824-58-8
3‐phosphopyruvate

A: 113-24-6
sodium pyruvate

B phosphate: phosphate

Conditions

Conditions	Yield
With acetate buffer In water at 75℃; Mechanism; Kinetics; Thermodynamic data; different buffers: pH 0.59 to 8.32; kH/kD; different temp.; Ea, ΔH(excit.), ΔS(excit.);

: Sodium; (2S,4S,5R,6S)-6-(1,2-dihydroxy-ethyl)-2,4,5-trihydroxy-tetrahydro-pyran-2-carboxylate

A: 608-47-9
β-D-lyxopyranose

B: 113-24-6
sodium pyruvate

Conditions

Conditions	Yield
With N-acetylneuraminic acid aldolase at 37℃;

Sodium Pyruvate Chemical Properties

IUPAC Name: Sodium 2-oxopropanoate
Synonyms of of Sodium Pyruvate (CAS NO.113-24-6): 2-Oxopropanoate de sodium ; Natrium-2-oxopropanoat ; Propanoic acid, 2-oxo-, sodium salt ; Propanoic acid, 2-oxo-, sodium salt (1:1) ; Sodium 2-oxopropanoate
Molecular Structure:
Molecular Formula: C₃H₃NaO₃
Molecular Weight: 110.04
CAS NO : 113-24-6
EINECS : 204-024-4
BRN : 3568341
H bond acceptors: 3
H bond donors: 1
Freely Rotating Bonds: 1
Polar Surface Area: 54.37 Å²
Flash Point: 54.3 °C
Enthalpy of Vaporization: 44.28 kJ/mol
Boiling Point: 165 °C at 760 mmHg
Vapour Pressure: 0.968 mmHg at 25°C
Melting Point: >300 °C(lit.)
Density: 1.267g/cm³
Refractive index: 1.426-1.43
Storage temp: 2-8°C
Solubility: H₂O: 100 mg/mL
Stability: Stable. Incompatible with strong oxidizing agents.
Appearance:White to slightly yellow crystalline powder
Product Categories of Sodium Pyruvate (CAS NO.113-24-6): FINE Chemical & INTERMEDIATES;PyruvicAcidSeries;Hybridoma Media SupplementsCell Culture;Hybridoma Platform;Miscellaneous Reagents and SupplementsNeural Stem Cell Biology;Neural Stem Cell Isolation/Expansion;Reagents and Supplements;Serum-free Media;Supplements/Reagents

Sodium Pyruvate Uses

Sodium Pyruvate (CAS NO.113-24-6) is commonly added to cell culture media as an additional source of energy, but may also have protective effects against hydrogen peroxide. This was reported by Giandomenico et al. and has been confirmed by several independent groups.

Sodium Pyruvate Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 36/37/39-26-24/25
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S24/25: Avoid contact with skin and eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
HS Code: 29183000

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