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Sodium Pyruvate

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Name

Sodium Pyruvate

EINECS 204-024-4
CAS No. 113-24-6 Density 1.267 g/cm3
PSA 57.20000 LogP -1.67470
Solubility water: 100 mg/mL Melting Point >300 °C(lit.)
Formula C3H3NaO3 Boiling Point 165 °C at 760 mmHg
Molecular Weight 110.04 Flash Point 54.3 °C
Transport Information Appearance White to slightly yellow crystalline powder
Safety 36/37/39-26-24/25 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 113-24-6 (Sodium pyruvate) Hazard Symbols IrritantXi
Synonyms

Propanoicacid, 2-oxo-, sodium salt (9CI);Pyruvic acid, sodium salt (7CI,8CI);Sodiumpyruvate;Sodium a-ketopropionate;

 

Sodium Pyruvate Synthetic route

127-17-3

2-oxo-propionic acid

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With sodium formate In ethyl acetate97%
With sodium acetate In ethyl acetate94%
With sodium hydroxide; ethanol; water
79-41-4

poly(methacrylic acid)

113-24-6

sodium pyruvate

Conditions
ConditionsYield
Stage #1: poly(methacrylic acid) With ozone In methanol; dichloromethane at -78℃;
Stage #2: With dimethylsulfide In methanol; dichloromethane at -78 - 20℃;
Stage #3: With sodium hydroxide In water
92%
97-64-3, 2676-33-7

ethyl 2-hydroxypropionate

113-24-6

sodium pyruvate

Conditions
ConditionsYield
Stage #1: ethyl 2-hydroxypropionate With 9-azabicyclo<3.3.1>nonane-N-oxyl; dihydrogen peroxide In ethyl acetate at 10 - 40℃; for 3h;
Stage #2: With sodium carbonate In water; ethyl acetate at 20℃; for 1h; pH=3 - 4; Reagent/catalyst; Temperature;
55%
56-41-7

L-alanin

114-76-1

sodium phenylphyruvate

A

150-30-1

Phenylalanine

B

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With acetate buffer; N(1+)C5His2C16; PL(1+)2C16; copper(II) perchlorate In water at 30℃; for 48h; Kinetics;
21593-77-1, 49621-03-6

S-allyl cysteine

A

2179-57-9

diallyl disulphide

B

539-86-6

allicin

C

29418-05-1

bis-2-propenyl thiosulfonate

D

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With nitrogen(II) oxide In water for 24h; Ambient temperature; Yield given. Yields of byproduct given;
44300-97-2

sodium enol pyruvate

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With sodium hydroxide; iodine; potassium iodide In water at 25℃; Rate constant; Equilibrium constant; other base as reagents;
With phosphate buffer; iodine; potassium iodide at 11℃; Equilibrium constant; Further Variations:; Temperatures; enolization;
43165-43-1

sodium pyruvate hydrate

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With sodium hydroxide In water at 25℃; Rate constant; Equilibrium constant; other bases or acids reagents;
With phosphate buffer; iodine; potassium iodide at 11℃; Equilibrium constant; Further Variations:; Temperatures; hydration;
312-85-6

sodium lactate

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With sodium hydroxide; lead(II) nitrate In water Product distribution; modified platinum electrode by lead ad-atoms, effect of pyruvate concentration;
With sodium ruthenate(VI); hexacyanoferrate(III); sodium perchlorate; sodium hydroxide at 30℃; Kinetics; Mechanism;
5824-58-8

3‐phosphopyruvate

A

113-24-6

sodium pyruvate

B

phosphate

phosphate

Conditions
ConditionsYield
With acetate buffer In water at 75℃; Mechanism; Kinetics; Thermodynamic data; different buffers: pH 0.59 to 8.32; kH/kD; different temp.; Ea, ΔH(excit.), ΔS(excit.);

Sodium; (2S,4S,5R,6S)-6-(1,2-dihydroxy-ethyl)-2,4,5-trihydroxy-tetrahydro-pyran-2-carboxylate

A

608-47-9

β-D-lyxopyranose

B

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With N-acetylneuraminic acid aldolase at 37℃;

Sodium; (2S,4S,5R,6R)-2,4,5-trihydroxy-6-(1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylate

A

7322-31-8

β-D-mannose

B

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With N-acetylneuraminic acid aldolase at 37℃;
Conditions
ConditionsYield
With N-acetylneuraminic acid aldolase at 37℃;
56-41-7

L-alanin

65-22-5

pyridoxal hydrochloride

A

113-24-6

sodium pyruvate

B

85-87-0

pyridoxamine

Conditions
ConditionsYield
Stage #1: L-alanin; pyridoxal hydrochloride With sodium acetate; acetic acid In ethanol; water at 50℃; pH=7.15;
Stage #2: In ethanol
1138160-36-7

sodium 4-phenyl-4-hydroxy-2-oxobutyrate

A

113-24-6

sodium pyruvate

B

100-52-7

benzaldehyde

Conditions
ConditionsYield
With bovine heart L-lactate dehydrogenase; C80H134N14O12; NADH at 30℃; for 14h; pH=8; Kinetics; pH-value; Temperature; Reagent/catalyst; aq. buffer; Enzymatic reaction;
2507-67-7

4-hydroxy-2-oxopentanoate

A

4-hydroxy-2-oxopentanoate

B

113-24-6

sodium pyruvate

C

75-07-0

acetaldehyde

Conditions
ConditionsYield
With pyruvate aldolase BphI; manganese(ll) chloride pH=8; aq. buffer;

sodium oxaloacetic acid

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With L-lactate dehydrogenase; NADH; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid pH=8; Kinetics; aq. buffer; Enzymatic reaction;

sodium 4-hydroxy-2-oxopentanoate

A

113-24-6

sodium pyruvate

B

75-07-0

acetaldehyde

Conditions
ConditionsYield
With L-lactate dehydrogenase; NADH; manganese(ll) chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid pH=8; Kinetics; aq. buffer; Enzymatic reaction;

sodium 4-hydroxy-2-oxohexanoate

A

113-24-6

sodium pyruvate

B

123-38-6

propionaldehyde

Conditions
ConditionsYield
With L-lactate dehydrogenase; NADH; manganese(ll) chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid pH=8; Kinetics; aq. buffer; Enzymatic reaction;

sodium 4-hydroxy-2-oxoheptanoate

A

113-24-6

sodium pyruvate

B

123-72-8

butyraldehyde

Conditions
ConditionsYield
With L-lactate dehydrogenase; NADH; manganese(ll) chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid pH=8; Kinetics; aq. buffer; Enzymatic reaction;

sodium 4-(S)-hydroxy-2-oxopentanoate

A

113-24-6

sodium pyruvate

B

75-07-0

acetaldehyde

Conditions
ConditionsYield
With L-lactate dehydrogenase; NADH; manganese(ll) chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid at 25℃; pH=8; Kinetics; aq. buffer; Enzymatic reaction;

sodium 4-(R)-hydroxy-2-oxopentanoate

A

113-24-6

sodium pyruvate

B

75-07-0

acetaldehyde

Conditions
ConditionsYield
With L-lactate dehydrogenase; NADH; manganese(ll) chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid at 25℃; pH=8; Kinetics; aq. buffer; Enzymatic reaction;

sodium 2-keto-4-hydroxyoctanoate

A

110-62-3

pentanal

B

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With L-lactate dehydrogenase; NADH; manganese(ll) chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid pH=8; Kinetics; aq. buffer; Enzymatic reaction;
920-49-0

D-(-)-sodium lactate

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With recombinant D-lactate dehydrogenase from Lactobacillus jensenii 269-3; nicotinamide adenine dinucleotide In aq. buffer at 25℃; pH=8; Kinetics; Concentration; Reagent/catalyst; Temperature; pH-value; Enzymatic reaction;
867-56-1

sodium L-lactate

113-24-6

sodium pyruvate

Conditions
ConditionsYield
With Aerococcus viridans L-lactate oxidase, wild-type, containing oxidized-state FMN cofactor In aq. phosphate buffer at 20℃; pH=6.5; Kinetics; Reagent/catalyst; Temperature; Flow reactor;
530-26-7

D-Mannose

113-24-6

sodium pyruvate

120104-31-6

(2S,4S,5R,6R)-2,4,5-Trihydroxy-6-((1R,2R)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid

Conditions
ConditionsYield
With Neu5Ac aldolase for 24h;100%
With sodium azide; potassium phosphate buffer; diothiothreitol at 37℃; for 24h; N-acetylneuraminate pyruvate lyase;84%
With sodium azide; diothiothreitol; acylneuraminate pyruvate lyase covalently bound to 4percent agarose In water at 37℃; for 24h; 0.05 M potassium phosphate buffer, pH 7.2;84%
With DL-dithiothreitol at 37℃; for 72h; NeuAc aldolase, potassium phosphate buffer, pH 7.5;78%
With sodium azide; potassium phosphate buffer; acylneuraminate pyruvate lyase; agarose; diothiothreitol at 37℃; for 24h; Yield given;
113-24-6

sodium pyruvate

56-41-7

L-alanin

Conditions
ConditionsYield
With sodium formate; ammonium chloride; NADH In aq. phosphate buffer at 25℃; for 6h; pH=8.0; Kinetics; Reagent/catalyst; Green chemistry; Enzymatic reaction;100%
With zinc(II) perchlorate; (R)-15-amino-methyl-14-hydroxy-5,5-dimethyl-2,8-dithia<9>(2,5)pyridinophane In methanol for 24h; Ambient temperature;72%
113-24-6

sodium pyruvate

1122-91-4

4-bromo-benzaldehyde

139005-22-4

(E)-4-(4-bromophenyl)-2-oxo-but-3-enoic acid

Conditions
ConditionsYield
With water; sodium hydroxide In ethanol at 20℃; for 1h; Knoevenagel Condensation; Inert atmosphere;100%
With potassium hydroxide In ethanol75%
Stage #1: sodium pyruvate; 4-bromo-benzaldehyde In methanol; water at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: With potassium hydroxide In methanol; water at 0 - 20℃; Inert atmosphere;
Stage #3: With hydrogenchloride In methanol; water pH=2; Inert atmosphere;
With potassium hydroxide In ethanol; water at 0℃; for 3h;
Conditions
ConditionsYield
With Neisseria meningitidis CMP-sialic acid synthetase; Escherichia coli K12 sialic acid aldolase; Pasteurella multocida sialyl transferase; cytidine triphosphate; magnesium chloride pH=8.5; aq. Tris-HCl buffer; Enzymatic reaction;100%

N-(2-benzyloxyacetyl)-d-mannosamine

113-24-6

sodium pyruvate

N-(2-benzyloxyacetyl)-D-neuraminic acid

Conditions
ConditionsYield
With Pasteurella multocida sialic acid aldolase In water at 37℃; for 48h; Enzymatic reaction; chemoselective reaction;100%
With sodium azide; sialic acid aldolase from Escherichia coli K1 In aq. phosphate buffer at 37℃; pH=7.6; Enzymatic reaction;63%
113-24-6

sodium pyruvate

312-85-6

sodium lactate

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In methanol at 25℃;100%
With [pentamethylcyclopentadienyl*Ir(N-phenyl-2-pyridinecarboxamidate)Cl]; sodium formate In methanol at 37℃; for 15h;100 %Spectr.
With cannabichromene; NADH; lactate dehydrogenase In aq. phosphate buffer Kinetics; Enzymatic reaction;
With tetrahydrocannabinolic acid; NADH; lactate dehydrogenase In aq. phosphate buffer Kinetics; Enzymatic reaction;
113-24-6

sodium pyruvate

N-(N-benzyloxycarbonyl-glycyl)-D-mannosamine

229954-81-8

3-azidopropyl (β-O-D-galactopyranosyl)-(1→4)-O-β-D-glucopyranoside

3-azidopropyl O-[5-(N-benzyloxycarboxyamino)glycylamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid]-(2->6)-O-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside

Conditions
ConditionsYield
With E. coli sialic acid aldolase; N. meningitidis CMP-sialic acid synthetase; Photobacterium damsela α-2,6-sialyltransferase; cytidine triphosphate; magnesium chloride In water pH=8.8;99%

N-methoxyacetate-D-mannosamine

113-24-6

sodium pyruvate

229954-81-8

3-azidopropyl (β-O-D-galactopyranosyl)-(1→4)-O-β-D-glucopyranoside

3-azidopropyl O-(5-methoxyacetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2->6)-O-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside

Conditions
ConditionsYield
With E. coli sialic acid aldolase; N. meningitidis CMP-sialic acid synthetase; Photobacterium damsela α-2,6-sialyltransferase; cytidine triphosphate; magnesium chloride In water pH=8.8;99%
113-24-6

sodium pyruvate

6-azido-6-deoxy-D-mannopyranose

methyl β-D-galactopyranosyl-(1->4)-O-2-acetamido-2-deoxy-β-D-glucopyranoside acceptor substrate

methyl β-D-galactopyranosyl-(1->4)-O-2-acetamido-2-deoxy-β-D-glucopyranoside acceptor substrate

methyl sodium [9-azido-3,9-dideoxy-D-glycero-α-D-galacto-2-nonulo-pyranosyl]-onate-(2->3)-(β-D-galactopyranosyl)-(1->4)-O-2-acetamido-2-deoxy-β-D-glucopyranoside

Conditions
ConditionsYield
Stage #1: sodium pyruvate; 6-azido-6-deoxy-D-mannopyranose With N. meningitidis ST3Gal-CMPNeu5Ac synthetase fusion protein; Neu5Ac-aldolase (Nal-311 (Toyobo); cytidine triphosphate In sodium hydroxide at 37℃; for 14h; pH=8.3 - 9.0; Enzymatic reaction;
Stage #2: methyl β-D-galactopyranosyl-(1->4)-O-2-acetamido-2-deoxy-β-D-glucopyranoside acceptor substrate With hydrogenchloride; recombinant sialyltransferase rat ST3Gal III; manganese(ll) chloride for 14h; pH=7.0; Enzymatic reaction; Further stages.;
98%
113-24-6

sodium pyruvate

229954-81-8

3-azidopropyl (β-O-D-galactopyranosyl)-(1→4)-O-β-D-glucopyranoside

3-azidopropyl O-(5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2->6)-O-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside

Conditions
ConditionsYield
With E. coli sialic acid aldolase; N. meningitidis CMP-sialic acid synthetase; Photobacterium damsela α-2,6-sialyltransferase; cytidine triphosphate; magnesium chloride In water pH=8.8;98%
113-24-6

sodium pyruvate

75-07-0

acetaldehyde

53584-56-8

(R)-acetoin

Conditions
ConditionsYield
With thiamine diphosphate In phosphate buffer at 30℃; pH=6.0;98%
113-24-6

sodium pyruvate

97604-58-5

2-azido-2-deoxy-D-mannopyranose

857642-16-1

(2S,3R,4S,5R,6R)-2-{[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-(prop-2-yn-1-yloxy)tetrahydro-2H-pyran-3-yl]oxy}-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

1196892-67-7

propargyl O-(5-azido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2->6)-O-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside

Conditions
ConditionsYield
With E. coli sialic acid aldolase; Photobacterium damsela α2,6-sialyltransferase; Neisseria meninigitidis CMP-sialic acid synthetase; cytidine-5’-triphosphate sodium salt; magnesium chloride at 20℃; for 15h; pH=8.5; aq. buffer; Enzymatic reaction;98%
113-24-6

sodium pyruvate

21732-98-9

1H-[1,2,4]triazole-3-carboxylic acid hydrazide

1353017-20-5

C6H6N5O3(1-)*Na(1+)

Conditions
ConditionsYield
In methanol for 24h; Reflux;98%

6-deoxy-6-fluoro-D-mannopyranose

113-24-6

sodium pyruvate

3150-24-1

4-nitrophenyl-β-D-galactopyranoside

C21H27FNO15(1-)*Na(1+)

Conditions
ConditionsYield
With Neisseria meningitidis CMP-sialic acid synthetase; cytidine 5′-triphosphate disodium salt; Pasteurella multocida sialic acid aldolase; Photobacterium damselae α2-6-sialyltransferase; magnesium chloride pH=8.5; aq. buffer; Enzymatic reaction;98%

2,6-dideoxy-2-glycolylamino-6-fluoro-D-mannopyranose

113-24-6

sodium pyruvate

3150-24-1

4-nitrophenyl-β-D-galactopyranoside

C23H30FN2O16(1-)*Na(1+)

Conditions
ConditionsYield
With Neisseria meningitidis CMP-sialic acid synthetase; cytidine 5′-triphosphate disodium salt; Pasteurella multocida sialic acid aldolase; Pasteurella multocida multifunctional α2-3-sialyltransferase; magnesium chloride pH=8.5; aq. buffer; Enzymatic reaction;98%
113-24-6

sodium pyruvate

74950-73-5, 74950-79-1, 77870-49-6

2-acetamido-2,6-dideoxy-6-fluoro-D-mannopyranose

3150-24-1

4-nitrophenyl-β-D-galactopyranoside

C23H30FN2O15(1-)*Na(1+)

Conditions
ConditionsYield
With Neisseria meningitidis CMP-sialic acid synthetase; cytidine 5′-triphosphate disodium salt; Pasteurella multocida sialic acid aldolase; Pasteurella multocida multifunctional α2-3-sialyltransferase; magnesium chloride pH=8.5; aq. buffer; Enzymatic reaction;98%
113-24-6

sodium pyruvate

2-acetamido-2,4-dideoxy-4-fluoro-D-mannopyranoside

3150-24-1

4-nitrophenyl-β-D-galactopyranoside

A

4-nitrophenyl O-(7-fluoro-5-acetamido-3,5,7-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2→3)-O-β-D-galactopyranoside

B

4-nitrophenyl O-(7-fluoro-5-acetamido-3,5,7-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2→6)-O-β-D-galactopyranoside

Conditions
ConditionsYield
With cytidine 5′-triphosphate disodium salt; neisseria meningitides CMP-sialicacid synthetase; pasteurella multocida sialic acidaldolase; magnesium chloride In aq. buffer at 37℃; Inert atmosphere; Enzymatic reaction;A 98%
B 92%

4-deoxy-4-fluoro-D-mannopyranoside

113-24-6

sodium pyruvate

3150-24-1

4-nitrophenyl-β-D-galactopyranoside

A

4-nitrophenyl O-(3,7-dideoxy-7-fluoro-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2→3)-O-β-D-galactopyranoside

B

4-nitrophenyl O-(3,9-dideoxy-7-fluoro-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2→6)-O-β-D-galactopyranoside

Conditions
ConditionsYield
With cytidine 5′-triphosphate disodium salt; neisseria meningitides CMP-sialicacid synthetase; pasteurella multocida sialic acidaldolase; magnesium chloride In aq. buffer at 37℃; Inert atmosphere; Enzymatic reaction;A 98%
B 95%
113-24-6

sodium pyruvate

2-acetamido-4-azido-2,4-dideoxy-D-mannopyranoside

3150-24-1

4-nitrophenyl-β-D-galactopyranoside

A

4-nitrophenyl O-(7-azido-5-acetamido-3,5,7-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2→6)-O-β-D-galactopyranoside

B

C23H30N5O15(1-)

Conditions
ConditionsYield
With cytidine 5′-triphosphate disodium salt; neisseria meningitides CMP-sialicacid synthetase; pasteurella multocida sialic acidaldolase; magnesium chloride In aq. buffer at 37℃; Inert atmosphere; Enzymatic reaction;A 98%
B 80%
113-24-6

sodium pyruvate

3150-24-1

4-nitrophenyl-β-D-galactopyranoside

4-azido-4-deoxy-D-mannopyranoside

A

4-nitrophenyl O-(7-azido-3,7-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2→3)-O-β-D-galactopyranoside

B

4-nitrophenyl O-(7-azido-3,7-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2→6)-O-β-D-galactopyranoside

Conditions
ConditionsYield
With cytidine 5′-triphosphate disodium salt; neisseria meningitides CMP-sialicacid synthetase; pasteurella multocida sialic acidaldolase; magnesium chloride In aq. buffer at 37℃; Inert atmosphere; Enzymatic reaction;A 98%
B 89%
19949-68-9, 37077-16-0, 60135-21-9

2,6-diacetamido-2,6-dideoxy-D-mannopyranose

1257307-68-8

3-azidopropyl β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-α-D-galactopyranoside

113-24-6

sodium pyruvate

3-azidopropyl O-(5,9-diacetamido-3,5,9-trideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2→6)-O-β-D-galactopyranosyl-(1→3)-2-acetamido-2-deoxy-α-D-galactopyranoside

Conditions
ConditionsYield
With CTP(3Na+); Neisseria meningitidis CMP-sialic acid synthetase; pasteurella multocida sialic acidaldolase; Photobacterium damselae α2-6 sialyltransferase; magnesium chloride In aq. buffer at 37℃; pH=7.5; Enzymatic reaction;98%
4419-94-7

4-nitrophenyl β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside

113-24-6

sodium pyruvate

4-nitrophenyl O-(5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonicacid)-(2→3)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside

Conditions
ConditionsYield
Stage #1: N-Acetyl-D-glucosamine; sodium pyruvate With Escherichia coli. ΔnanTEK/pNA; magnesium chloride In aq. buffer at 30℃; for 16h; Enzymatic reaction;
Stage #2: 4-nitrophenyl β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside With cytidine 5’-monophosphate-Sia synthetase; sialyltransferase Pm2,3ST; cytidine triphosphate at 25℃; for 2h;
98%
4419-94-7

4-nitrophenyl β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside

113-24-6

sodium pyruvate

4-nitrophenyl O-(5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonicacid)-(2→6)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside

Conditions
ConditionsYield
Stage #1: N-Acetyl-D-glucosamine; sodium pyruvate With Escherichia coli. ΔnanTEK/pNA; magnesium chloride In aq. buffer at 30℃; for 16h; Enzymatic reaction;
Stage #2: 4-nitrophenyl β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside With cytidine 5’-monophosphate-Sia synthetase; sialyltransferase Pd2,6ST; cytidine triphosphate at 25℃; for 2h;
98%
1152-39-2, 28244-98-6, 121523-95-3, 131488-68-1

p-methylphenyl-1-thio-β-D-galactopyranoside

2,4-diazido-2,4,6-trideoxy-D-mannose

113-24-6

sodium pyruvate

C22H29N6O10S(1-)

Conditions
ConditionsYield
With Neisseria meningitidis CMP-sialic acid synthetase; Pasteurella multocida sialic acid aldolase; Pasteurella multocida sialyltransferase 1 M144D mutant; cytidine triphosphate; magnesium chloride In water at 30℃; for 48h; Reagent/catalyst; Enzymatic reaction;98%
1152-39-2, 28244-98-6, 121523-95-3, 131488-68-1

p-methylphenyl-1-thio-β-D-galactopyranoside

2,4-diazido-2,4,6-trideoxy-D-mannose

113-24-6

sodium pyruvate

C22H30N6O10S

Conditions
ConditionsYield
With Neisseria meningitidis CMP-sialic acid synthetase; Pasteurella multocida sialic acid aldolase; pasteurella multocida 2-3-sialyltransferase 1 M144D mutant; cytidine triphosphate; magnesium chloride In water at 30℃; for 48h; pH=8.5; Enzymatic reaction;98%
113-24-6

sodium pyruvate

123-11-5

4-methoxy-benzaldehyde

potassium (E)-4-(4-methoxyphenyl)-2-oxobut-3-enoate

Conditions
ConditionsYield
With potassium hydroxide In methanol at 0 - 25℃;98%
530-26-7

D-Mannose

113-24-6

sodium pyruvate

229954-81-8

3-azidopropyl (β-O-D-galactopyranosyl)-(1→4)-O-β-D-glucopyranoside

3-azidopropyl O-(3-deoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid)-(2->6)-O-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside

Conditions
ConditionsYield
With E. coli sialic acid aldolase; N. meningitidis CMP-sialic acid synthetase; Photobacterium damsela α-2,6-sialyltransferase; cytidine triphosphate; magnesium chloride In water pH=8.8;97%

N-methoxyacetate-D-mannosamine

113-24-6

sodium pyruvate

3150-24-1

4-nitrophenyl-β-D-galactopyranoside

4-nitrophenyl O-[5-(2-methoxyacetamido)-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic acid]-(2->6)-O-β-D-galactopyranoside

Conditions
ConditionsYield
With Neisseria meningitidis CMP-sialic acid synthetase; Pasturella multocida sialic acid aldolase; Photobacterium damsela α2-6-sialyltransferase; magnesium chloride; cytidine 5'-triphosphate disodium salt In water at 37℃; pH=8.8; aq. Tris-HCl buffer; Enzymatic reaction;97%
113-24-6

sodium pyruvate

87-48-9

5-Bromo-1H-indole-2,3-dione

250641-14-6

6-bromoquinoline-2 ,4-dicarboxylic acid

Conditions
ConditionsYield
With sodium hydroxide In water for 4h; Reflux; Inert atmosphere;97%
With water; sodium hydroxide at 110℃; under 4500.45 Torr; for 0.166667h; Microwave irradiation;92%
With sodium hydroxide In water at 110℃; under 3750.38 Torr; for 0.333333h; Microwave irradiation;81.1%

Sodium Pyruvate Chemical Properties

IUPAC Name: Sodium 2-oxopropanoate
Synonyms of of Sodium Pyruvate (CAS NO.113-24-6): 2-Oxopropanoate de sodium ; Natrium-2-oxopropanoat ; Propanoic acid, 2-oxo-, sodium salt ; Propanoic acid, 2-oxo-, sodium salt (1:1) ; Sodium 2-oxopropanoate
Molecular Structure:
Molecular Formula: C3H3NaO3
Molecular Weight: 110.04
CAS NO : 113-24-6
EINECS : 204-024-4
BRN : 3568341
H bond acceptors: 3
H bond donors: 1
Freely Rotating Bonds: 1
Polar Surface Area: 54.37 Å2
Flash Point: 54.3 °C
Enthalpy of Vaporization: 44.28 kJ/mol
Boiling Point: 165 °C at 760 mmHg
Vapour Pressure: 0.968 mmHg at 25°C
Melting Point: >300 °C(lit.)
Density: 1.267g/cm3
Refractive index: 1.426-1.43
Storage temp: 2-8°C
Solubility: H2O: 100 mg/mL
Stability: Stable. Incompatible with strong oxidizing agents.
Appearance:White to slightly yellow crystalline powder
Product Categories of Sodium Pyruvate (CAS NO.113-24-6): FINE Chemical & INTERMEDIATES;PyruvicAcidSeries;Hybridoma Media SupplementsCell Culture;Hybridoma Platform;Miscellaneous Reagents and SupplementsNeural Stem Cell Biology;Neural Stem Cell Isolation/Expansion;Reagents and Supplements;Serum-free Media;Supplements/Reagents

Sodium Pyruvate Uses

 Sodium Pyruvate (CAS NO.113-24-6) is commonly added to cell culture media as an additional source of energy, but may also have protective effects against hydrogen peroxide. This was reported by Giandomenico et al. and has been confirmed by several independent groups.

Sodium Pyruvate Safety Profile

Hazard Codes: IrritantXi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 36/37/39-26-24/25
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S24/25: Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
WGK Germany: 3
HS Code: 29183000

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