ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity)

Synthesis Column chromatography QSAR (quantitative structure-activity relationship) Heterocyclic compounds In vitro Selectivity Derivatives Molecular docking Chiral center Lead compound Biological activities Molecular modeling Mass spectrometry (MS) IC50 Pharmacophore Scaffold Cytotoxicity binding affinity antimicrobial agents Minimum inhibitory concentration (MIC) HPLC (high-performance liquid chromatography) NMR (nuclear magnetic resonance) X-ray crystallography Enantiomeric purity Enzyme inhibition in vivo Inhibitor Purification In vitro Testing In Vivo Testing Clinical Development Biological Evaluation In Vivo Studies Lead Optimization Selective Inhibitors Zone of Inhibition Design Virtual Screening Docking Studies In Vitro Assays Resistance Structure-Activity Relationship (SAR) Antiviral Activity Enzyme Kinetics Drug Resistance Drug Repurposing Chirality High-Throughput Screening (HTS) MIC Determination Thiazole