The oxidative cyclization is the key step in the synthesis. o-Cinnamyl phenol is typically reacted with an oxidant like DDQ in an appropriate solvent and under suitable conditions. This reaction converts the o-cinnamyl phenol into the benzo[b]furan ring system. DDQ is a powerful oxidizing agent and can promote the formation of the furan ring by removing hydrogen atoms from the precursor.
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(E)-1-(4-(2-bromoethyloxy)phenyl)-3-phenylprop-2-en-1-one
ethyl 4-benzoyl-6-methyl-2-phenylquinoline-3-carboxylate
2-Pyridinecarboxaldehyde, (4-phenyl-2-thiazolyl)hydrazone
N-(2,2-dimethoxyethyl)-N-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-p-toluenesulfonamide
1-(3-(trifluoromethyl)phenyl)-3-(2,2-dimethylpent-4-enyl)urea
5-methoxy-2-(4-methylphenyl)-1H-indole
