Journal of Organic Chemistry p. 3411 - 3424 (2017)
Update date:2022-07-30
Topics: Characterization Purification Functional group manipulation Workup Deprotection (if necessary) Protection of Hydroxyl Group (if necessary) Oxidative Cyclization Dehydration (if necessary)
Rehan, Mohammad
Nallagonda, Rajender
Das, Braja Gopal
Meena, Tannu
Ghorai, Prasanta
Disclosed herein is an efficient synthetic route for the synthesis of functionalized 2-benzyl benzo[b]furans via a regioselective 5-exo-trig intramolecular oxidative cyclization of ortho-cinnamyl phenols using [PdCl2(CH3CN)2] as catalyst and benzoquinone as an oxidant. Further, a sequential ortho-cinnamylation of phenols using cinnamyl alcohols catalyzed by Re2O7, followed by an oxidative cyclization using the above Pd catalyst, is performed. The reaction showed broad substrate scope with good to excellent yields.
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Doi:10.1080/10426500490475166
(2004)Doi:10.1021/jm00036a016
(1994)Doi:10.1021/jm00014a008
(1995)Doi:10.1016/S0040-4020(01)85382-5
(1994)Doi:10.1021/op500025v
(2014)Doi:10.1039/c4dt00287c
(2014)