Spirocyclic Compound

A bicyclic structure where two rings share a single carbon atom (spiro center).

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Synthesis IR spectroscopy Pharmacological evaluation Regioselectivity Column chromatography Melting point Yield NMR spectroscopy Bioassay Chiral center Stereochemistry Thermolysis Chromatography Recrystallization Mass spectrometry (MS) IC50 Optically active Ketone Enantiomers Optical rotation Resolution X-ray crystallography Diastereomers Purification In vitro Testing In Vivo Testing Reaction Mechanism Circular Dichroism (CD) Cycloaddition Structure-Activity Relationship (SAR) Chiral HPLC Ring-Opening Reaction Activation Energy Reaction Optimization Thermal Transformations Spectroscopic Analysis Kinetic Control Thermodynamic Control Absolute Configuration Substituent Racemic mixture Rearrangement Reaction 8-substituted Polarimetry Benzylidene Antihypertensive Activity Rotamers 5]undecane Diradical intermediate Hypertension

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