Products Categories
| CAS No.: | 109384-19-2 |
|---|---|
| Name: | N-BOC-4-Hydroxypiperidine |
| Article Data: | 179 |
| Cas Database | |
| Molecular Structure: | |
|
|
|
| Formula: | C10H19NO3 |
| Molecular Weight: | 201.266 |
| Synonyms: | 1,1-Dimethylethyl4-hydroxypiperidine-1-carboxylate;1-(tert-Butoxycarbonyl)-4-hydroxypiperidine;1-(tert-Butyloxycarbonyl)piperidin-4-ol;1-Boc-4-hydroxypiperidine;1-Boc-piperidin-4-ol;1-tert-Butoxycarbonyl-4-piperidinol;1-tert-Butyloxycarbonyl-4-hydroxypiperidine;4-Hydroxy-1-(tert-butoxycarbonyl)piperidine;4-Hydroxy-1-piperidinecarboxylicacid tert-butyl ester;4-Hydroxy-N-(tert-butoxycarbonyl)piperidine;4-Hydroxy-N-Boc-piperidine;4-Hydroxypiperidine-1-carboxylic acid tert-butylester;N-(tert-Butoxycarbonyl)-4-hydroxypiperidine;N-(tert-Butoxycarbonyl)piperidin-4-ol;N-(tert-Butyloxycarbonyl)-4-hydroxypiperidine;N-(tert-Butyloxycarbonyl)-4-piperidinol;N-Boc-4-hydroxy-1-piperidine;N-Boc-4-piperidinol;tert-Butyl4-hydroxy-1-piperidinecarboxylate;1-Piperidinecarboxylicacid, 4-hydroxy-, 1,1-dimethylethyl ester; |
| EINECS: | -0 |
| Density: | 1.107 g/cm3 |
| Melting Point: | 60-65 ºC |
| Boiling Point: | 292.3 ºC at 760 mmHg |
| Flash Point: | 130.6 ºC |
| Appearance: | white or off-white crystalline powder |
| Hazard Symbols: |
 Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 26-37/39 |
| PSA: | 49.77000 |
| LogP: | 1.31610 |
- 1093847-94-9Phenol, 3-[2-[2-[[3-(S-methylsulfonimidoyl)phenyl]amino]-5-pyrimidinyl]ethynyl]-
- 109-38-6Octadecanoic acid,2-butoxyethyl ester
- 109389-24-42(1H)-Pyrimidinone,1-(2-deoxy-b-D-erythro-pentofuranosyl)-4-(1H-1,2,4-triazol-1-yl)-
- 109389-25-52(1H)-Pyrimidinone,1-(2-deoxy-b-D-erythro-pentofuranosyl)-5-methyl-4-(1H-1,2,4-triazol-1-yl)-
- 1093951-55-3cis-3-Methylcyclobutanamine hydrochloride
- 1093951-66-66-methoxy-4-methyl pyridine-3-boronic acid pinacol ester
- 109-39-79-Octadecenoic acid(9Z)-, 2-butoxyethyl ester
- 1093980-57-41H-Imidazole, 1-(4-ethynyl-2-methoxyphenyl)-4-methyl-
- 1094042-01-9CYM 5442
- 1094067-13-6SCH1473759 (HCl salt)
- 5382-16-1
4-HYDROXYPIPERIDINE
- 24424-99-5
di-tert-butyl dicarbonate
- 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
| With sodium hydroxide In water; tert-butyl alcohol at 20℃; | 100% |
| With sodium carbonate In dichloromethane; water for 72h; | 100% |
| With sodium carbonate In dichloromethane; water for 72h; Inert atmosphere; | 100% |
- 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one
- 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
| With sodium tetrahydroborate In ethanol | 100% |
| Stage #1: N-tert-butyloxycarbonylpiperidin-4-one With sodium tetrahydroborate In ethanol at 0 - 20℃; for 4h; Stage #2: With water; ammonium chloride In ethanol | 100% |
| With sodium hydroxide; sodium borohydrid In methanol | 100% |
- 5382-16-1
4-HYDROXYPIPERIDINE
- 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
| With tert-butyldicarbonate; triethylamine In dichloromethane at 0℃; for 21h; | 100% |
- 5382-16-1
4-HYDROXYPIPERIDINE
- 34619-03-9
tert-butyldicarbonate
- 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
| With sodium hydrogencarbonate In dichloromethane for 15h; | 100% |
| In tetrahydrofuran at 20℃; | 98.3% |
| With triethylamine In tetrahydrofuran at 20℃; | 98.3% |
- 24424-99-5
di-tert-butyl dicarbonate
- 5382-17-2
piperidin-4-ol hydrochloride
- 144-55-8
sodium hydrogencarbonate
- 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
| In 1,4-dioxane | 100% |
| In 1,4-dioxane | 100% |
- 626-64-2
pyridin-4-ol
- 24424-99-5
di-tert-butyl dicarbonate
- 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
| Stage #1: pyridin-4-ol With chloro(1,5-cyclooctadiene)rhodium(I) dimer; borane-ammonia complex In 2,2,2-trifluoroethanol at 50℃; for 24h; Inert atmosphere; Schlenk technique; Sealed tube; Stage #2: di-tert-butyl dicarbonate With triethylamine In 2,2,2-trifluoroethanol at 20℃; Inert atmosphere; Schlenk technique; Sealed tube; | 99% |
- 5382-16-1
4-HYDROXYPIPERIDINE
- 201230-82-2
carbon monoxide
- 75-65-0
tert-butyl alcohol
- 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
| With 2C7H9N4*Au(1+)*Cu(1+)*2I(1-) In toluene at 90℃; for 8h; Autoclave; | 98% |
- 24424-99-5
di-tert-butyl dicarbonate
- 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
| With triethylamine In tetrahydrofuran; ethyl acetate | 95% |
| Multi-step reaction with 2 steps 1: triethylamine / water; 1,4-dioxane / 0 - 20 °C 2: sodium tetrahydroborate; methanol / 0 - 20 °C View Scheme | |
| Multi-step reaction with 2 steps 1: triethylamine / dichloromethane / 0.8 h / 0 - 20 °C 2: sodium tetrahydroborate; methanol / 0.01 h / 0 - 20 °C View Scheme |
- 24424-99-5
di-tert-butyl dicarbonate
A
- 75844-69-8
t-butyl piperidinecarboxylate
B
- 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
| With triethylamine In tetrahydrofuran; ethyl acetate | A n/a B 94% |
| With triethylamine In tetrahydrofuran; ethyl acetate | A n/a B 94% |
| With triethylamine In tetrahydrofuran; ethyl acetate | A n/a B 94% |
- 1311186-22-7
tert-butyl 4-((4-methoxybenzyl)oxy)piperidine-1-carboxylate
- 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate
| Conditions | Yield |
|---|---|
| With N,N,N,N-tetraethylammonium tetrafluoroborate In methanol Electrochemical reaction; | 81% |
What can I do for you?
Get Best Price
Chemistry
The Molecular Structure of N-BOC-4-Hydroxypiperidine (CAS NO.109384-19-2):
Empirical Formula: C10H19NO3
Molecular Weight: 201.2628
IUPAC Name: tert-butyl 4-hydroxypiperidine-1-carboxylate
Appearance: White to cream powder
storage temp. Store at -15°C
Nominal Mass: 201 Da
Average Mass: 201.2628 Da
Monoisotopic Mass: 201.136493 Da
Index of Refraction: 1.495
Molar Refractivity: 53.03 cm3
Molar Volume: 181.6 cm3
Surface Tension: 42.5 dyne/cm
Density: 1.107 g/cm3
Flash Point: 130.6 °C
Enthalpy of Vaporization: 61.7 kJ/mol
Boiling Point: 292.3 °C at 760 mmHg
Vapour Pressure: 0.000198 mmHg at 25°C
Product Categories: Alcohols and Derivatives;Amines and Anilines;pharmacetical;Pyrans, Piperidines &Piperazines;Piperidine;Heterocyclic Compounds;Piperidines;Pyrans, Piperidines & Piperazines
Uses
N-BOC-4-Hydroxypiperidine (CAS NO.109384-19-2) is used as pharmaceutical intermediates.
Safety Profile
Hazard Codes: 
Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36-37/39
S26: In case of contact with eyes, rinse immediately with plenty of WATER and seek medical advice.
S36: Wear suitable protective clothing
S37/39: Wear suitable gloves and eye/face protection
WGK Germany: 3
Hazard Note: Irritant
HazardClass: IRRITANT
Specification
N-BOC-4-Hydroxypiperidine (CAS NO.109384-19-2) is also called as Tert-butyl 4-hydroxypiperidine-1-carboxylate ; Tert-butyl 4-hydroxy-1-piperidinecarboxylate ; N-(tert-butoxycarbonyl)-4-hydroxypiperidine ; N-(tert-butoxycarbonyl)-4-piperidinol ; N-boc-4-piperidinol ; N-boc-4-hydroxypiperidine ; N-boc-4-hydroxylpiperidine .