CAS No.2380-94-1,4-Hydroxyindole Suppliers,MSDS download

Products Categories

Pharmaceutical (204)
Organic Chemicals (48)
Others (11)
Reagent (7)
Materials (6)
Catalyst and Auxiliary (3)
Synthetic Flavours & Fragrances (2)
Basic Inorganic Chemicals (1)

Basic Information

Molecular Structure:
CAS No.:	2380-94-1
Name:	4-Hydroxyindole
Article Data:	40

Formula:	C₈H₇NO
Molecular Weight:	133.15
Synonyms:	1,5-Dihydro-indol-4-one;1,5-dihydroindol-4-one;1H-Indol-4-ol;4-Hydroxy Indole (4-Indolol);4-hydroxy-1H-indole;4-Hydroxy Indole;
EINECS:	219-177-2
Density:	1.327 g/cm³
Melting Point:	97-99 °C(lit.)
Boiling Point:	343.2 °C at 760 mmHg
Flash Point:	161.4 °C
Solubility:	slightly soluble
Appearance:	off-white cyrstalline solid
Hazard Symbols:	Xi
Risk Codes:	36/37/38
Safety:	26-36/37/39
PSA:	36.02000
LogP:	1.87350

Synthetic route

: 195992-07-5
3-nitro-2-vinylphenol

: 2380-94-1
1H-indol-4-ol

Conditions

Conditions	Yield
With carbon monoxide; triphenylphosphine; palladium diacetate In acetonitrile under 3040 Torr; Heating;	96%
With carbon monoxide; palladium diacetate; triphenylphosphine In acetonitrile at 90℃; under 3051.25 Torr; for 50h;	96%

: 95969-15-6
(4-Hydroxy-indol-1-yl)-phenyl-methanone

: 2380-94-1
1H-indol-4-ol

Conditions

Conditions	Yield
With potassium hydroxide at 0 - 20℃; for 2h;	96%

: C10H9NO2

: 2380-94-1
1H-indol-4-ol

Conditions

Conditions	Yield
With sodium hydroxide at 0℃; for 1h;	95%

: 20289-26-3
4-benzyloxy-1H-indole

: 2380-94-1
1H-indol-4-ol

Conditions

Conditions	Yield
With palladium on activated charcoal; hydrogen In methanol at 20℃; under 775.743 Torr; for 12h;	89.4%
With methanol; magnesium hydrosilicate; palladium Hydrogenation;

: 85926-99-4
4-hydroxyindoline

: 2380-94-1
1H-indol-4-ol

Conditions

Conditions	Yield
With palladium on activated charcoal In o-xylene for 2.3h; Heating;	88%

: (E)-6-benzyloxy-2-nitro-β-pyrrolidinostyrene

A: 2380-94-1
1H-indol-4-ol

B: 20289-26-3
4-benzyloxy-1H-indole

Conditions

Conditions	Yield
With hydrogen; 5% rhodium-on-charcoal; nickel(II) nitrate In tetrahydrofuran; water at 20℃; for 32h;	A 6% B 88%
With hydrogen; 5% rhodium-on-charcoal; iron(II) acetate In tetrahydrofuran at 20℃; for 31h;	A 5% B 83%
With hydrogen; 5% rhodium-on-charcoal; tris(acetylacetonato)cobalt In tetrahydrofuran at 20℃; for 38h;	A 3% B 80%

: 112970-68-0
4-acetoxy-N-tosylindole

: 2380-94-1
1H-indol-4-ol

Conditions

Conditions	Yield
With sodium hydroxide In methanol for 12h; Heating;	83%

: 79966-73-7
2-(2-benzyloxy-6-nitrophenyl)acetonitrile

: 2380-94-1
1H-indol-4-ol

Conditions

Conditions	Yield
With hydrogen; acetic acid; 10% palladium on active carbon In ethanol under 2280 Torr; for 2h; Ambient temperature;	81%
With palladium 10% on activated carbon; hydrogen; acetic acid In ethanol	78%

: 13754-86-4
1,5,6,7-tetrahydro-indol-4-one

A: 2380-94-1
1H-indol-4-ol

B: 5192-23-4
4-amino-1H-indole

Conditions

Conditions	Yield
With ethene; 5%-palladium/activated carbon; ammonium acetate In acetonitrile at 90℃; under 760.051 Torr; for 15h; Reagent/catalyst; Schlenk technique;	A 11% B 80%

: 75201-78-4
ethyl 4-hydroxy-1H-indole-1-carboxylate

: 2380-94-1
1H-indol-4-ol

Conditions

Conditions	Yield
palladium on activated charcoal	75%

Raw Materials

Downstream Products

Total:193 Page 1 of 6 1 2 3 4 5 6 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 2380-94-1

Chemistry

IUPAC Name: 1H-indol-4-ol
Synonyms of 4-Hydroxyindole (CAS NO.2380-94-1): 4-Indolol
CAS NO: 2380-94-1
Molecular Formula: C₈H₇NO
Molecular Weight: 133.15
Molecular Structure:
EINECS: 219-177-2
H bond acceptors: 2
H bond donors: 2
Freely Rotating Bonds: 1
Polar Surface Area: 14.16 Å²
Index of Refraction: 1.739
Molar Refractivity: 40.41 cm³
Molar Volume: 100.3 cm³
Surface Tension: 65.8 dyne/cm
Density: 1.327 g/cm³
Flash Point: 161.4 °C
Enthalpy of Vaporization: 61.03 kJ/mol
Boiling Point: 343.2 °C at 760 mmHg
Vapour Pressure: 3.61E-05 mmHg at 25°C
Melting Point: 97-99 °C(lit.)
Storage temp: 0-6°C
Water Solubility: slightly soluble
Sensitive: Air Sensitive
Appearance: Off-White Cyrstalline Solid
SMILES: c1cc2c(cc[nH]2)c(c1)O
InChI: InChI=1/C8H7NO/c10-8-3-1-2-7-6(8)4-5-9-7/h1-5,9-10H
InChIKey: NLMQHXUGJIAKTH-UHFFFAOYAU
Std. InChI: InChI=1S/C8H7NO/c10-8-3-1-2-7-6(8)4-5-9-7/h1-5,9-10H
Std. InChIKey: NLMQHXUGJIAKTH-UHFFFAOYSA-N
Product Categories of 4-Hydroxyindole (CAS NO.2380-94-1): blocks;IndolesOxindoles;Indoles and derivatives;pharmacetical;Heterocycles series;Pyrroles & Indoles;Indole;Indoles;Indole Derivatives;Simple Indoles;Chiral Compound;Pyrroles & Indoles

Uses

4-Hydroxyindole (CAS NO.2380-94-1) is used for pharmaceutical intermediates.

Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany: 3
Hazard Note: Irritant
HazardClass: IRRITANT

Specification

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Store 4-Hydroxyindole (CAS NO.2380-94-1) in a tightly closed container. Store in a dry area. Keep refrigerated. (Store below 4°C/39°F.) Store under nitrogen.