CAS No.76-37-9,Tetrafluoro-1-propanol Suppliers

Products Categories

Pharmaceutical (89)
Organic Chemicals (32)
Synthetic Flavours & Fragrances (20)
Reagent (8)
Others (7)
Materials (3)
Adhesive and Sealant (3)
Food Additives (2)
Agrochemicals (1)
Dyestuff and Pigment (1)
Basic Inorganic Chemicals (1)

Basic Information

Molecular Structure:
CAS No.:	76-37-9
Name:	Tetrafluoro-1-propanol
Article Data:	18
Cas Database

Formula:	C₃H₄F₄O
Molecular Weight:	132.058
Synonyms:	1,1,3-Trihydroperfluoro-1-propanol;2,2,3,3-Tetrafluoropropyl alcohol;2,2,3,3-tetrafluoro-porpanol;1-Propanol, 2,2,3,3-tetrafluoro-;2,2,3,3-Tetrafluoropropanol-1;1,1, 3-Trihydroperfluoro-1-propanol;Tetrafluoropropyl alcohol;4-01-00-01438 (Beilstein Handbook Reference);2,2,3,3-Tetrafluoropropan-1-ol;2, 2,3,3-Tetrafluoropropyl alcohol;2,2,3,3-Tetrafluoro-1-propanol (TFP);1H,1H,3H-Tetrafluoro-1-propanol;2,2,3,3-tetrafluoro-1-propanol;;Tetrafluoropropanol;Trans-4-ethyl Hexahydrobenzoic Acid;2,2,3,3-Tetrafluoro-Propanol;2,2,3,3-Tetrafluoro-1-Propanol(Tfp);
EINECS:	200-955-5
Density:	1.35 g/cm³
Melting Point:	-15 °C
Boiling Point:	109.5 °C at 760 mmHg
Flash Point:	31 °C
Solubility:	Soluble in water.
Appearance:	colourless liquid
Hazard Symbols:	Xn, F, Xi
Risk Codes:	10-20-36-36/37/38
Safety:	26-37/39-16-36/37-36
Transport Information:	UN 1986 3/PG 3
PSA:	20.23000
LogP:	0.87910

Synthetic route

: 65611-25-8
phosphonic acid bis-(2,2,3,3-tetrafluoro-propyl) ester

: 121-44-8
triethylamine

A: 76-37-9
2,2,3,3-tetrafluoropropanol

B: triethylammonium hydrogen 1H,1H,3H-tetrafluoropropyl phosphite

Conditions

Conditions	Yield
With water for 1h; Ambient temperature;	A 96.4% B 88.6%

...Expand

: 3,5-Bis-(1,1,2,2-tetrafluoro-ethyl)-2,2,2-tris-(2,2,3,3-tetrafluoro-propoxy)-2λ5-[1,4,2]dioxaphospholane

A: 76-37-9
2,2,3,3-tetrafluoropropanol

B: 756-04-7
2,2,3,3-tetrafluoropropionaldehyde

C: (2,2,3,3-Tetrafluoro-1-hydroxy-propyl)-phosphonic acid bis-(2,2,3,3-tetrafluoro-propyl) ester

Conditions

Conditions	Yield
With water In acetone at 20℃; for 20h;	A n/a B n/a C 95%

...Expand

: 302-17-0
chloral hydrate

: 87651-42-1
di(1,1,3-trihydrotetrafluoropropyl)phenyl phosphonite

A: 76-37-9
2,2,3,3-tetrafluoropropanol

B: 1235818-80-0
(1,1,3-trihydrotetrafluoropropyl) (1-hydroxy-2,2,2-trichloroethyl)phenylphosphinate

Conditions

Conditions	Yield
In benzene at 30 - 40℃; for 12h; Abramov reaction; Inert atmosphere;	A n/a B 95%

...Expand

: 2648-47-7
2,2,3,3,4,4,5,5-octafluorovaleraldehyde

: 2241-68-1
tris(2,2,3,3-tetrafluoropropyl)phosphite

A: 76-37-9
2,2,3,3-tetrafluoropropanol

B: bis(2,2,3,3-tetrafluoropropyl) (1H,5H-octafluoro-1-hydroxypentyl)phosphonate

Conditions

Conditions	Yield
In benzene at 20 - 25℃; for 2h;	A n/a B 92%

...Expand

: 71879-02-2
pentakis(2,2,3,3-tetrafluoropropoxy)phosphorane

: 106-54-7
p-Chlorothiophenol

A: 563-10-0
phosphoric acid tris-(2,2,3,3-tetrafluoro-propyl ester)

B: 76-37-9
2,2,3,3-tetrafluoropropanol

C: 1-Chloro-4-(2,2,3,3-tetrafluoro-propylsulfanyl)-benzene

Conditions

Conditions	Yield
at 150℃; for 4h;	A n/a B n/a C 72%

...Expand

: 302-17-0
chloral hydrate

: C7H9F8O2P

A: 76-37-9
2,2,3,3-tetrafluoropropanol

B: 111257-11-5
O-(1,1,3-trihydrotetrafluoropropyl)-(1-hydroxy-2,2,2-trichloroethyl)methylphosphinate

C: (1-hydroxy-2,2,2-trichloroethyl)methylphosphinic acid

Conditions

Conditions	Yield
In benzene for 12h; Heating;	A n/a B 70% C n/a

...Expand

: 71879-02-2
pentakis(2,2,3,3-tetrafluoropropoxy)phosphorane

: 106-53-6
para-bromobenzenethiol

A: 563-10-0
phosphoric acid tris-(2,2,3,3-tetrafluoro-propyl ester)

B: 76-37-9
2,2,3,3-tetrafluoropropanol

C: 1-Bromo-4-(2,2,3,3-tetrafluoro-propylsulfanyl)-benzene

Conditions

Conditions	Yield
at 150℃; for 4h;	A n/a B n/a C 70%

...Expand

: 71879-02-2
pentakis(2,2,3,3-tetrafluoropropoxy)phosphorane

: 108-98-5
thiophenol

A: 563-10-0
phosphoric acid tris-(2,2,3,3-tetrafluoro-propyl ester)

B: 76-37-9
2,2,3,3-tetrafluoropropanol

C: 2,2,3,3-tetrafluoropropylphenyl sulfide

Conditions

Conditions	Yield
at 150℃; for 4h;	A n/a B n/a C 63.5%

...Expand

: 71879-02-2
pentakis(2,2,3,3-tetrafluoropropoxy)phosphorane

: 106-45-6
para-thiocresol

A: 563-10-0
phosphoric acid tris-(2,2,3,3-tetrafluoro-propyl ester)

B: 76-37-9
2,2,3,3-tetrafluoropropanol

C: 1-Methyl-4-(2,2,3,3-tetrafluoro-propylsulfanyl)-benzene

Conditions

Conditions	Yield
at 150℃; for 4h;	A n/a B n/a C 60%

...Expand

: 2,2,2-Tris-(2,2,3,3-tetrafluoro-propoxy)-3,5-bis-trifluoromethyl-2λ5-[1,4,2]dioxaphospholane

A: 76-37-9
2,2,3,3-tetrafluoropropanol

B: 75-90-1
2,2,2-Trifluoroacetaldehyde

C: 88332-81-4
(2,2,2-Trifluoro-1-hydroxy-ethyl)-phosphonic acid bis-(2,2,3,3-tetrafluoro-propyl) ester

Conditions

Conditions	Yield
With water In acetone at 20℃; for 20h;	A n/a B n/a C 56%

...Expand

Raw Materials

302-17-0

108-98-5

2241-68-1

116-14-3

67-56-1

Downstream Products

756-09-2

359-35-3

628-13-7

67-66-3

Total:128 Page 1 of 4 1 2 3 4 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 76-37-9

Consensus Reports

Reported in EPA TSCA Inventory.

Specification

The 2,2,3,3-Tetrafluoro-1-propanol, with the cas registry number 76-37-9, has the systematic name of 2,2,3,3-tetrafluoropropan-1-ol. This is a kind of stable chemical, and it is incompatible with strong oxidizing agents, strong bases, sodium, potassium, acid chlorides, acid anhydrides. Its product categories are various, including industrial/fine chemicals; small molecule; organic fluorides; alcohols; c2 to c6; oxygen compounds.

The characteristics of this chemical are as follows: (1)#H bond acceptors: 1; (2)#H bond donors: 1; (3)#Freely Rotating Bonds: 3; (4)Polar Surface Area: 20.23; (5)Index of Refraction: 1.296; (6)Molar Refractivity: 18.06 cm³; (7)Molar Volume: 97.7 cm³; (8)Polarizability: 7.16 ×10^-24 cm³; (9)Surface Tension: 17 dyne/cm; (10)Density: 1.35 g/cm³; (11)Flash Point: 31 °C; (12)Enthalpy of Vaporization: 40.59 kJ/mol; (13)Boiling Point: 109.5 °C at 760 mmHg; (14)Vapour Pressure: 13.1 mmHg at 25°C; (15)Exact Mass: 132.019828; (16)MonoIsotopic Mass: 132.019828; (17)Topological Polar Surface Area: 20.2; (18)Heavy Atom Count: 8; (19)Complexity: 71.7.

Use of 2,2,3,3-Tetrafluoro-1-propanol is as below: 2,2,3,3-Tetrafluoro-1-propanol could react to produce 3-chloro-1,1,2,2-tetrafluoro-propane, with the following condition: reagent: (2-chloro-1,1,2-trifluoro-ethyl)-diethyl-amin; reaction temp.: 170 ℃.

As to its usage, it is widely applied in many ways. It is usually used in pharmaceutics, intermediate for pesticide, light disk paint solvent, and cleaning agent.

When dealing with this chemical, you should be cautious and then take some measures to protect yourself. For one thing, it is irritant. This chemical is irritating to eyes, respiratory system and skin. For another thing, it is harmful, and may cause damage to health. In addition, it is highly flammable. It may catch fire in contact with air, only needing brief contact with an ignition source, and it has a very low flash point or evolve highly flammable gases in contact with water. Therefore, you should take the following instructions. Wear suitable clothing, gloves and eye/face protection, and keep away from sources of ignition - No smoking. If in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

Additionally, the following data information could be converted into the molecular structure:
(1)SMILES:FC(F)C(F)(F)CO
(2)InChI:InChI=1/C3H4F4O/c4-2(5)3(6,7)1-8/h2,8H,1H2
(3)InChIKey:NBUKAOOFKZFCGD-UHFFFAOYAL

Below are the toxicity information of this chemical:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LC50	inhalation	8600mg/m3/2H (8600mg/m3)		"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 109, 1982.
rat	LCLo	inhalation	2000ppm/4H (2000ppm)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS	Journal of Occupational Medicine. Vol. 4, Pg. 262, 1962.
rat	LDLo	oral	3400mg/kg (3400mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES GASTROINTESTINAL: OTHER CHANGES	Journal of Occupational Medicine. Vol. 4, Pg. 262, 1962